Mast cells (MCs) are immunocytes with secretory functions that act locally in peripheral
tissues to modulate local hemodynamics, nociceptor activation and pain. They are also able …

Objective To investigate the suburothelial inflammation and urothelial dysfunction that
occurs with ketamine-related cystitis (KC) and interstitial cystitis/bladder pain syndrome …

PURPOSE: We characterized pharmacological effects of the phytotherapeutic agent
Eviprostat® on urodynamic parameters, bladder muscarinic and purinergic receptors, and …

Background Interstitial cystitis (IC), more recently called painful bladder syndrome (PBS) is a
complex disease associated with chronic bladder inflammation that primarily affects women …

Interstitial cystitis (IC) is a disease of undetermined etiology and pathogenesis. Inflammation
is thought to play a key role in many patients, characteristically with an increase in mast cells …

Objective To evaluate the effect of the R ho kinase inhibitor, hydroxyfasudil, on bladder
function in a rat model of HCl‐induced chemical cystitis, and to elucidate the possible …

Purpose We established the physiological relevance of LL-37 induced bladder
inflammation. We hypothesized that 1) human urinary LL-37 is increased in pediatric …

The pathogenesis of interstitial cystitis/painful bladder syndrome (IC/PBS) is multifactorial,
but likely involves urothelial cell dysfunction and mast cell accumulation in the bladder wall …

Interstitial Cystitis/Painful Bladder Syndrome is a controversial chronic disease
characterized by pain, urgency and frequency. Patients with severe symptoms have a very …

目的: 分析探讨采用经尿道膀胱腔内神经阻滞注射方式治疗间质性膀胱炎的有效性和可行性.
方法: 分析回顾2010 年7 月~ 2011 年11 月收治的女性间质性膀胱炎患者16 例临床资料 …