Sex differences in autism spectrum disorders

DM Werling, DH Geschwind - Current opinion in neurology, 2013 - journals.lww.com
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The genetic landscapes of autism spectrum disorders

G Huguet, E Ey, T Bourgeron - Annual review of genomics and …, 2013 - annualreviews.org
The autism spectrum disorders (ASD) are characterized by impairments in social interaction
and stereotyped behaviors. For the majority of individuals with ASD, the causes of the …

A compendium of RNA-binding motifs for decoding gene regulation

D Ray, H Kazan, KB Cook, MT Weirauch… - Nature, 2013 - nature.com
RNA-binding proteins are key regulators of gene expression, yet only a small fraction have
been functionally characterized. Here we report a systematic analysis of the RNA motifs …

[HTML][HTML] Integrative functional genomic analyses implicate specific molecular pathways and circuits in autism

NN Parikshak, R Luo, A Zhang, H Won, JK Lowe… - Cell, 2013 - cell.com
Genetic studies have identified dozens of autism spectrum disorder (ASD) susceptibility
genes, raising two critical questions:(1) do these genetic loci converge on specific biological …

[HTML][HTML] Spatial and temporal mapping of de novo mutations in schizophrenia to a fetal prefrontal cortical network

S Gulsuner, T Walsh, AC Watts, MK Lee, AM Thornton… - Cell, 2013 - cell.com
Genes disrupted in schizophrenia may be revealed by de novo mutations in affected
persons from otherwise healthy families. Furthermore, during normal brain development …

Microglial activation in young adults with autism spectrum disorder

K Suzuki, G Sugihara, Y Ouchi, K Nakamura… - JAMA …, 2013 - jamanetwork.com
Context A growing body of evidence suggests that aberrant immunologic systems underlie
the pathophysiologic characteristics of autism spectrum disorder (ASD). However, to our …

Impaired thalamocortical connectivity in autism spectrum disorder: a study of functional and anatomical connectivity

A Nair, JM Treiber, DK Shukla, P Shih, RA Müller - Brain, 2013 - academic.oup.com
The thalamus plays crucial roles in the development and mature functioning of numerous
sensorimotor, cognitive and attentional circuits. Currently limited evidence suggests that …

Clinical features, neurogenetics and neuropathology of the polyglutamine spinocerebellar ataxias type 1, 2, 3, 6 and 7

U Rüb, L Schöls, H Paulson, G Auburger… - Progress in …, 2013 - Elsevier
The spinocerebellar ataxias type 1 (SCA1), 2 (SCA2), 3 (SCA3), 6 (SCA6) and 7 (SCA7) are
genetically defined autosomal dominantly inherited progressive cerebellar ataxias (ADCAs) …

Cytokine dysregulation in autism spectrum disorders (ASD): possible role of the environment

PE Goines, P Ashwood - Neurotoxicology and teratology, 2013 - Elsevier
Autism spectrum disorders (ASD) are neurodevelopmental diseases that affect an alarming
number of individuals. The etiological basis of ASD is unclear, and evidence suggests it …

Altered neural connectivity in excitatory and inhibitory cortical circuits in autism

B Zikopoulos, H Barbas - Frontiers in human neuroscience, 2013 - frontiersin.org
Converging evidence from diverse studies suggests that atypical brain connectivity in autism
affects in distinct ways short-and long-range cortical pathways, disrupting neural …