SAMHD1 host restriction factor: a link with innate immune sensing of retrovirus infection

A Sze, D Olagnier, R Lin, J van Grevenynghe… - Journal of molecular …, 2013 - Elsevier
SAMHD1 [sterile alpha motif and histidine-aspartic domain (HD) containing protein 1] is the
most recent addition to a unique group of host restriction factors that limit retroviral …

SAMHD1 knockout mice: modeling retrovirus restriction in vivo

L Wu - Retrovirology, 2013 - Springer
The host dNTP hydrolase SAMHD1 acts as a viral restriction factor to inhibit the replication of
several retroviruses and DNA viruses in non-cycling human immune cells. However …