Aging is associated with a dysregulation of the immune response, loosely termed
“immunosenescence.” Each part of the immune system is influenced to some extent by the …

Inflamm-aging, that is the age-associated inflammatory status, is considered one of the most
striking consequences of immunosenescence, as it is believed to be linked to the majority of …

Abstract Serum, cerebrospinal fluid (CSF), and cryopreserved lymphocytes from subjects in
the Rush Alzheimer's Disease Center Religious Orders Study were analyzed for …

Influenza vaccination is less effective in the elderly compared to the young. Studies that
have attempted to identify immune parameters correlating with satisfactory vaccine …

Exercise immunology is an important, emerging sub-discipline within exercise physiology,
concerned with the relationship between exercise, immune function and infection risk. This …

In this prospective study we analyzed pretransplant interferon-γ secretion by
cytomegalovirus (CMV)-specific CD8+ T cells to assess its possible utility in determining the …

Publication of a report from the Institute of Medicine in 2000 showing that a vaccine against
cytomegalovirus (CMV) would likely be cost saving was very influential and encouraged the …

Cytomegalovirus (CMV) infection leads to the development of adaptive and humoral
immune responses that are among the largest for any pathogen, and intriguingly, the …

The mechanisms regulating memory CD8+ T cell function and homeostasis during aging are
unclear. CD8+ effector memory T cells that re-express CD45RA increase considerably in …

Human herpesviruses including cytomegalovirus, Epstein–Barr virus, HHV6, HHV7, HHV8,
Herpes simplex virus (HSV)-1 and HSV-2 and varicella zoster virus (VZV) have developed …