Maternal age≥ 45 years and maternal and perinatal outcomes: a review of the evidence
M Carolan - Midwifery, 2013 - Elsevier
OBJECTIVE: to examine the evidence in relation to very advanced maternal age (≥ 45
years) and maternal and perinatal outcomes in high-income countries. BACKGROUND: this …
years) and maternal and perinatal outcomes in high-income countries. BACKGROUND: this …
A critical review of methods to evaluate the impact of FDA regulatory actions
Purpose To conduct a synthesis of the literature on methods to evaluate the impacts of FDA
regulatory actions and identify best practices for future evaluations. Methods We searched …
regulatory actions and identify best practices for future evaluations. Methods We searched …
Tamsulosin treatment for benign prostatic hyperplasia and risk of severe hypotension in men aged 40-85 years in the United States: risk window analyses using …
Objective To characterize risk of hypotension requiring admission to hospital in middle aged
and older men treated with tamsulosin for benign prostatic hyperplasia. Design Population …
and older men treated with tamsulosin for benign prostatic hyperplasia. Design Population …
Orlistat and the risk of acute liver injury: self controlled case series study in UK Clinical Practice Research Datalink
IJ Douglas, J Langham, K Bhaskaran, R Brauer… - Bmj, 2013 - bmj.com
Objective To measure the association between orlistat and acute liver injury. Design Self
controlled case series study. Setting Population based primary care setting, United …
controlled case series study. Setting Population based primary care setting, United …
An evaluation of the THIN database in the OMOP Common Data Model for active drug safety surveillance
X Zhou, S Murugesan, H Bhullar, Q Liu, B Cai… - Drug safety, 2013 - Springer
Background There has been increased interest in using multiple observational databases to
understand the safety profile of medical products during the postmarketing period. However …
understand the safety profile of medical products during the postmarketing period. However …
Medication‐wide association studies
Undiscovered side effects of drugs can have a profound effect on the health of the nation,
and electronic health‐care databases offer opportunities to speed up the discovery of these …
and electronic health‐care databases offer opportunities to speed up the discovery of these …
Population-based analysis of non-steroidal anti-inflammatory drug use among children in four European countries in the SOS project: what size of data platforms and …
VE Valkhoff, R Schade, GW 't Jong, S Romio… - BMC pediatrics, 2013 - Springer
Background Data on utilization patterns and safety of non-steroidal anti-inflammatory drugs
(NSAIDs) in children are scarce. The purpose of this study was to investigate the utilization …
(NSAIDs) in children are scarce. The purpose of this study was to investigate the utilization …
Proton pump inhibitors and the risk of pneumonia: a comparison of cohort and self-controlled case series designs
EN Ramsay, NL Pratt, P Ryan… - BMC medical research …, 2013 - Springer
Background To compare the results of a new-user cohort study design and the self-
controlled case series (SCCS) design using the risk of hospitalisation for pneumonia in …
controlled case series (SCCS) design using the risk of hospitalisation for pneumonia in …
Safety of a tetanus-diphtheria-acellular pertussis vaccine when used off-label in an elderly population
HF Tseng, LS Sy, L Qian, SM Marcy… - Clinical infectious …, 2013 - academic.oup.com
Background. Published data on the safety of tetanus-diphtheria-acellular pertussis vaccine
(Tdap) in persons aged≥ 65 years are limited. This study aims to examine a large cohort of …
(Tdap) in persons aged≥ 65 years are limited. This study aims to examine a large cohort of …
Suicide-related events in young people following prescription of SSRIs and other antidepressants: a self-controlled case series analysis
Objectives We aimed to examine the temporal association between selective serotonin
reuptake inhibitors (SSRI) and tricyclic antidepressant (TCA) prescriptions and suicide …
reuptake inhibitors (SSRI) and tricyclic antidepressant (TCA) prescriptions and suicide …