Diabetes is a metabolic disease and is a major cause of mortality and morbidity in epidemic
proportions. A type I diabetic patient is dependent on daily injections of insulin, for survival …

Plasma glucose levels are maintained within a narrow range in normal individuals. Both
insulin-dependent and insulin-independent processes contribute to fasting and postprandial …

OBJECTIVE To compare efficacy and safety of lixisenatide once daily versus exenatide
twice daily in type 2 diabetes inadequately controlled with metformin. RESEARCH DESIGN …

Glucagon‐like peptide‐1 (GLP‐1) and peptide YY (PYY), secreted by enteroendocrine L‐
cells located most densely in the colon and rectum, are of fundamental importance in blood …

Due to the increasing prevalence of type 2 diabetes mellitus (T2DM), the emergent trend
towards diagnosis in younger patients and the progressive nature of this disease, many …

Aims/hypothesis Type 2 diabetes mellitus is associated with reduced incretin effects.
Although previous studies have shown that hyperglycaemia contributes to impaired incretin …

Aim To investigate durability of efficacy and safety over 1 year of the sequence of liraglutide
added to metformin followed by add-on insulin detemir if glycated hemoglobin (HbA 1c) …

Background Delayed gastric emptying limits the administration of enteral nutrition, leading to
malnutrition, which is associated with higher mortality and morbidity. Currently available …

An important role in the regulation of glucose homeostasis is played by incretins, which are
gut-derived hormones released in response to nutrient ingestion. In humans, the major …

Glucagon-like peptide-1 (GLP-1) receptor agonists are one of the newer classes of
medications for the treatment of adults with type 2 diabetes. The GLP-1 receptor agonist …