New Delhi metallo-beta-lactamase (NDM-1) is a novel metallo-beta-lactamase (MBL).
Sporadic cases of NDM-1 positive strains have been reported from different countries …

Metallo-β-lactamases (MBLs) are a growing threat to the use of almost all clinically used β-
lactam antibiotics. The identification of broad-spectrum MBL inhibitors is hampered by the …

Mass spectrometry-based platforms have gained increasing success in discovery of ligands
bound to therapeutic targets as drug candidates. We established both a nanoelectrospray …

Due to the global threat of antibiotic resistance mediated by New Delhi metallo-beta-
lactamase-1 (NDM-1) and the lack of structurally diverse inhibitors reported for this enzyme …

New Delhi metallo-β-lactamase (NDM-1) is a new metallo-β-lactamase (MBL) that has
recently emerged as a global threat because it confers bacteria with resistance to almost all …

Metallo-β-lactamases can hydrolyze and deactivate lactam-containing antibiotics, which is
the major mechanism for causing drug resistance in the treatment of bacterial infections …

New Delhi metallo-β-lactmase-1 (NDM-1) has recently attracted extensive attention for its
biological activities to catalyze the hydrolysis of almost all of β-lactam antibiotics. To study …

New Delhi metallo-β-lactmase-1 (NDM-1) has attracted extensive attention for its high
catalytic activities of hydrolyzing almost all β-lactam antibiotics. NDM-1 shows relatively …

Three new polyketide compounds (1–3), a new quinolone alkaloid (4), and seven known
polyketide derivatives were identified from the cultures of Penicillium sp. I09F 484, a strain …

New Delhi metallo-β-lactamase-1 (NDM-1) has emerged as a major global threat to human
health for its rapid rate of dissemination and ability to make pathogenic microbes resistant to …