Particle deposition in a child's nasal cavity is much different than that in the nasal airway of
an adult because of the differences in geometry and breathing patterns. However, most …

An idealized geometry of the infant nasal airways is developed with the goal of mimicking
the average inertial filtration of aerosols by the nasal passages. Paramount geometrical …

High prevalence of pulmonary diseases in childhood requires inhalable medication even for
young children. Little is known about the efficiency of aerosol therapy especially in …

Nine oral airway replicas of children 6–14 years old were used for measuring deposition of
0.5–6.3 μm diameter particles during inhalation of four representative (sinusoidal) breathing …

Anatomically accurate computational fluid dynamics (CFD) models of the nasal passages of
an infant (6 months old, 1.3 kg) and adult (7 years old, 11.9 kg) rhesus monkey were used to …

The purpose of this study is to explore the topical use of radiographic contrast agents to
enhance soft-tissue contrast on cone beam CT (CBCT) images. Different barium sulphate …

Existing pharmacopeial methods for the in vitro testing of orally inhaled products (OIPs) are
simplified representations of clinical reality, as their objective is to provide metrics that are …

The previous chapters have focused primarily on the application of AIM-EDA in the quality
control part of an OIP lifecycle. An AIM-based approach would also be desirable for …

Many patients, particularly the very young, the elderly and those with co-morbidities affecting
coordination, need to use a facemask rather than a mouthpiece in order to receive inhaled …