Indazoles: a new top seed structure in the search of efficient drugs against Trypanosoma cruzi
B Aguilera-Venegas, C Olea-Azar, VJ Aran… - Future Medicinal …, 2013 - Taylor & Francis
For years, Chagas disease treatment has been limited to only two drugs of highly
questionable and controversial use (Nifurtimox® and Benznidazole®). In the search of …
questionable and controversial use (Nifurtimox® and Benznidazole®). In the search of …
Novel quinoxaline 1, 4-di-N-oxide derivatives as new potential antichagasic agents
E Torres, E Moreno-Viguri, S Galiano… - European journal of …, 2013 - Elsevier
As a continuation of our research and with the aim of obtaining new agents against Chagas
disease, an extremely neglected disease which threatens 100 million people, eighteen new …
disease, an extremely neglected disease which threatens 100 million people, eighteen new …
Ligand-based design, synthesis, and experimental evaluation of novel benzofuroxan derivatives as anti-Trypanosoma cruzi agents
SD Jorge, F Palace-Berl, KFM Pasqualoto… - European journal of …, 2013 - Elsevier
A set of substituted-[N′-(benzofuroxan-5-yl) methylene] benzohydrazides (4a–t), previously
designed and synthesized, was experimentally assayed against Trypanosoma cruzi, the …
designed and synthesized, was experimentally assayed against Trypanosoma cruzi, the …
Synthesis of Substituted 1H-Indazoles by Pyrazole Annelation to an Arene
AK Garkushenko, OP Sorokina, GA Kryuchkova… - Chemistry of …, 2013 - Springer
Substituted 1 H-indazoles have been synthesized by reductive intramolecular
heterocyclization of 2, 4-di-aroyl-N-nitrosomethylanilines and 2, 4-diacetyl-N …
heterocyclization of 2, 4-di-aroyl-N-nitrosomethylanilines and 2, 4-diacetyl-N …
Una nueva estrategia basada en el diseño de fármacos multidiana para el tratamiento de enfermedades neurodegenerativas
PJ González Naranjo - 2013 - docta.ucm.es
UNIVERSIDAD COMPLUTENSE DE MADRID FACULTAD DE FARMACIA UNA NUEVA
ESTRATEGIA BASADA EN EL DISEÑO DE FÁRMACOS MULTIDIANA PARA Page 1 …
ESTRATEGIA BASADA EN EL DISEÑO DE FÁRMACOS MULTIDIANA PARA Page 1 …
Diseño, síntesis y evaluación biológica de nuevos derivados de 1, 4-di-N-óxido de quinoxalina como potenciales agentes antichagásicos
E Torres - 2013 - dadun.unav.edu
El principal objetivo de este trabajo es el diseño y síntesis de nuevos derivados de
quinoxalina 1, 4-di-N-óxido que curen la enfermedad de Chagas. La estrategia seguida …
quinoxalina 1, 4-di-N-óxido que curen la enfermedad de Chagas. La estrategia seguida …
СИНТЕЗ ЗАМЕЩЁННЫХ 1Н-ИНДАЗОЛОВ ДОСТРОЙКОЙ ПИРАЗОЛЬНОГО ЦИКЛА
АК Гаркушенко, ОП Сорокина… - Chemistry of …, 2013 - 5.179.29.131
Восстановительной внутримолекулярной гетероциклизацией N-нитрозометил-2, 4-
диароиланилинов и N-нитрозометил-2, 4-диацетиланилина синтезированы …
диароиланилинов и N-нитрозометил-2, 4-диацетиланилина синтезированы …