Mechanosensitive microRNAs—role in endothelial responses to shear stress and redox state
T Marin, B Gongol, Z Chen, B Woo… - Free Radical Biology …, 2013 - Elsevier
Endothelial functions are highly regulated by imposed shear stress in vivo. The
characteristics of shear stress determine mechanotransduction events that regulate …
characteristics of shear stress determine mechanotransduction events that regulate …
miRNA regulatory variation in human evolution
J Li, Z Zhang - Trends in Genetics, 2013 - cell.com
Recent advancements have revealed a complex post-transcriptional regulatory network in
humans involving miRNAs. However, the contribution of miRNAs to human evolution …
humans involving miRNAs. However, the contribution of miRNAs to human evolution …
miRNA-29c suppresses lung cancer cell adhesion to extracellular matrix and metastasis by targeting integrin β1 and matrix metalloproteinase2 (MMP2)
H Wang, Y Zhu, M Zhao, C Wu, P Zhang, L Tang… - PloS one, 2013 - journals.plos.org
Our pilot study using miRNA arrays found that miRNA-29c (miR-29c) is differentially
expressed in the paired low-metastatic lung cancer cell line 95C compared to the high …
expressed in the paired low-metastatic lung cancer cell line 95C compared to the high …
The inhibitory role of Mir-29 in growth of breast cancer cells
Z Wu, X Huang, X Huang, Q Zou, Y Guo - Journal of experimental & clinical …, 2013 - Springer
Mir-29 microRNA families are involved in regulation of various types of cancers. Although
Mir-29 was shown to play an inhibitory role in tumorigenesis, the role of Mir-29 in breast …
Mir-29 was shown to play an inhibitory role in tumorigenesis, the role of Mir-29 in breast …
MicroRNA and cancer chemoprevention
MicroRNAs (miRNA) are a group of naturally occurring, small, noncoding, and single-strand
RNA molecules that regulate gene expression at the posttranscriptional and translational …
RNA molecules that regulate gene expression at the posttranscriptional and translational …
A systems level predictive model for global gene regulation of methanogenesis in a hydrogenotrophic methanogen
Methanogens catalyze the critical methane-producing step (called methanogenesis) in the
anaerobic decomposition of organic matter. Here, we present the first predictive model of …
anaerobic decomposition of organic matter. Here, we present the first predictive model of …
Repression of bone morphogenetic protein 4 by let-7i attenuates mesenchymal migration of head and neck cancer cells
The movement modes of epithelial cancer cells in three-dimensional (3D) environments
include the mesenchymal mode, which is associated with local invasion, and the amoeboid …
include the mesenchymal mode, which is associated with local invasion, and the amoeboid …
Inferring the perturbed microRNA regulatory networks in cancer using hierarchical gene co-expression signatures
MicroRNAs (miRNAs), a class of endogenous small regulatory RNAs, play important roles in
many biological and physiological processes. The perturbations of some miRNAs, which are …
many biological and physiological processes. The perturbations of some miRNAs, which are …
microRNAs, new players in cancer chemoprevention
B Yi, Y Xi - microRNAs in Toxicology and Medicine, 2013 - Wiley Online Library
The biogenesis of microRNAs (miRNAs) is similar to the other RNAs starting from DNA
transcription. The immature primary miRNAs (pri‐miRNAs) are yielded by the transcription of …
transcription. The immature primary miRNAs (pri‐miRNAs) are yielded by the transcription of …
[PDF][PDF] 癌症基因异常甲基化标记的鉴定
摘要DNA 甲基化在肿瘤的发展中起着重要的作用. 以前的研究已经确定了癌症和正常对照组之
间甲基化位点(DMS) 的差异, 但是, 甲基化在多发性癌症中的变异并没有被发现. 在这项研究中 …
间甲基化位点(DMS) 的差异, 但是, 甲基化在多发性癌症中的变异并没有被发现. 在这项研究中 …