From SARS to MERS: 10 years of research on highly pathogenic human coronaviruses

R Hilgenfeld, M Peiris - Antiviral research, 2013 - Elsevier
This article introduces a series of invited papers in Antiviral Research marking the 10th
anniversary of the outbreak of severe acute respiratory syndrome (SARS), caused by a …

Cell host response to infection with novel human coronavirus EMC predicts potential antivirals and important differences with SARS coronavirus

L Josset, VD Menachery, LE Gralinski, S Agnihothram… - MBio, 2013 - Am Soc Microbiol
ABSTRACT A novel human coronavirus (HCoV-EMC) was recently identified in the Middle
East as the causative agent of a severe acute respiratory syndrome (SARS) resembling the …

Assessing activity and inhibition of Middle East respiratory syndrome coronavirus papain-like and 3C-like proteases using luciferase-based biosensors

A Kilianski, AM Mielech, X Deng, SC Baker - Journal of virology, 2013 - Am Soc Microbiol
Middle East respiratory syndrome coronavirus (MERS-CoV) is associated with an outbreak
of more than 90 cases of severe pneumonia with high mortality (greater than 50%). To date …

[HTML][HTML] Is MERS another SARS?

C Drosten - The Lancet. Infectious Diseases, 2013 - ncbi.nlm.nih.gov
Abdullah Assiri and colleagues3 provide a clinical synopsis of 47 cases of MERS-CoV
infection identified between September, 2012, and June, 2013, in Saudi Arabia. This work …

[PDF][PDF] Assessing activity and inhibition of MERS-CoV papain-like and 3C-like proteases using luciferase-based biosensors

A Kilianski, A Mielech, X Deng, SC Baker - J Virol, 2013 - academia.edu
Middle East Respiratory Syndrome coronavirus (MERS-CoV) is associated with an outbreak
of 21 more than 90 cases of severe pneumonia with high mortality (greater than 50%). To …

[HTML][HTML] Coronavirus: need for a therapeutic approach

B Guery, S van der Werf - The Lancet. Infectious Diseases, 2013 - ncbi.nlm.nih.gov
Between March and July, 2003, a global outbreak of severe acute respiratory syndrome
(SARS) caused more than 8000 probable or confirmed cases and 774 deaths in 25 …

[PDF][PDF] Trabajo Fin de Máster

CG Pérez - Málaga, 2013 - academia.edu
Entre mis múltiples intereses intelectuales, está el de la lectura de libros sobre lingüística y
cognición, y es justamente en un libro de Steven Pinker, El instinto del lenguaje. Cómo crea …

Coronaviral Polyprotein Nsp7-10: Proteolytic Processing and Dynamic Interactions within the Transcriptase/Replicase Complex

S Falke - 2013 - ediss.sub.uni-hamburg.de
Coronaviruses (CoVs) comprise a group of enveloped (-) ssRNA viruses. SARS-CoV and
the currently emerging MERS-CoV characterized by a fatality rate of around 50% are …

以MERS-CoV 主蛋白酶为靶点的药物筛选体系的建立及应用

张宁, 潘丽, 牛国君, 王文明, 周红刚… - 中国生物工程 …, 2013 - manu60.magtech.com.cn
目的: 以新型冠状病毒(MERS-CoV) 主蛋白酶NSP5 为靶点, 应用荧光共振能量转移法(FRET)
建立药物筛选体系, 并进行抑制剂的筛选. 方法: 采用原核表达系统, 利用基因重组以及蛋白表达 …