Mounting evidence indicates that inflammatory cytokines contribute to the development of
depression in both medically ill and medically healthy individuals. Cytokines are important …

There is considerable evidence that stressful early life events influence a variety of physical
health problems later in life. Childhood adversity has been linked to elevated rates of …

Childhood maltreatment is likely to influence fundamental biological processes and engrave
long-lasting epigenetic marks, leading to adverse health outcomes in adulthood. We aimed …

There is increasing interest in discovering mechanisms that mediate the effects of childhood
stress on late-life disease morbidity and mortality. Previous studies have suggested one …

BACKGROUND: Retrospective studies show that childhood adversity is associated with
systemic inflammation in adulthood. Few prospective studies have examined whether …

BACKGROUND: Child abuse is highly prevalent and associated with increased risk for a
range of health problems, including cancer, cardiovascular disease, diabetes, psychiatric …

Many young people who are mistreated by an adult, victimized by bullies, criminally
assaulted, or who witness domestic violence react to this violence exposure by developing …

An inflammatory syndrome has been previously reported in chronic schizophrenia. The aims
of this study were to investigate:(1) serum levels and leukocyte gene expression of cytokines …

BACKGROUND: Children exposed to early life adversity (ELA) have been shown to have
elevated circulating concentrations of inflammatory markers that persist into adulthood …

Variability in response to stressful environmental exposures is at the core of resilience
research. In order to understand why some individuals show resilient functioning in the face …