Structural perspective on the formation of ribonucleoprotein complex in negative-sense single-stranded RNA viruses

H Zhou, Y Sun, Y Guo, Z Lou - Trends in microbiology, 2013 - cell.com
Negative-sense single-stranded RNA viruses (NSRVs) possess a ribonucleoprotein (RNP)
complex composed of viral polymerase and genomic RNA surrounded by viral …

Discovery of a unique novel clade of mosquito-associated bunyaviruses

M Marklewitz, F Zirkel, IB Rwego, H Heidemann… - Journal of …, 2013 - Am Soc Microbiol
Bunyaviruses are the largest known family of RNA viruses, infecting vertebrates, insects, and
plants. Here we isolated three novel bunyaviruses from mosquitoes sampled in Côte …

Nucleocapsid protein structures from orthobunyaviruses reveal insight into ribonucleoprotein architecture and RNA polymerization

A Ariza, SJ Tanner, CT Walter, KC Dent… - Nucleic Acids …, 2013 - academic.oup.com
All orthobunyaviruses possess three genome segments of single-stranded negative sense
RNA that are encapsidated with the virus-encoded nucleocapsid (N) protein to form a …

Structural basis for encapsidation of genomic RNA by La Crosse Orthobunyavirus nucleoprotein

J Reguera, H Malet, F Weber… - Proceedings of the …, 2013 - National Acad Sciences
The nucleoprotein (NP) of segmented negative-strand RNA viruses such as Orthomyxo-,
Arena-, and Bunyaviruses coats the genomic viral RNA and together with the polymerase …

Structure of severe fever with thrombocytopenia syndrome virus nucleocapsid protein in complex with suramin reveals therapeutic potential

L Jiao, S Ouyang, M Liang, F Niu, N Shaw… - Journal of …, 2013 - Am Soc Microbiol
Severe fever with thrombocytopenia syndrome is an emerging infectious disease caused by
a novel bunyavirus (SFTSV). Lack of vaccines and inadequate therapeutic treatments have …

Structure of the Leanyer orthobunyavirus nucleoprotein–RNA complex reveals unique architecture for RNA encapsidation

F Niu, N Shaw, YE Wang, L Jiao… - Proceedings of the …, 2013 - National Acad Sciences
Negative-stranded RNA viruses cover their genome with nucleoprotein (N) to protect it from
the human innate immune system. Abrogation of the function of N offers a unique …

Structure of Schmallenberg orthobunyavirus nucleoprotein suggests a novel mechanism of genome encapsidation

H Dong, P Li, RM Elliott, C Dong - Journal of virology, 2013 - Am Soc Microbiol
Schmallenberg virus (SBV), a newly emerged orthobunyavirus (family Bunyaviridae), has
spread rapidly across Europe and has caused congenital abnormalities in the offspring of …

Bunyamwera virus possesses a distinct nucleocapsid protein to facilitate genome encapsidation

B Li, Q Wang, X Pan… - Proceedings of the …, 2013 - National Acad Sciences
Bunyamwera virus (BUNV), which belongs to the genus Orthobunyavirus, is the prototypical
virus of the Bunyaviridae family. Similar to other negative-sense single-stranded RNA …

The nucleoprotein of severe fever with thrombocytopenia syndrome virus processes a stable hexameric ring to facilitate RNA encapsidation

H Zhou, Y Sun, Y Wang, M Liu, C Liu, W Wang… - Protein & …, 2013 - academic.oup.com
Severe fever with thrombocytopenia syndrome virus (SFTSV), a member of the Phlebovirus
genus from the Bunyaviridae family endemic to China, is the causative agent of life …

The crystal structure and RNA-binding of an orthomyxovirus nucleoprotein

W Zheng, J Olson, V Vakharia, YJ Tao - PLoS pathogens, 2013 - journals.plos.org
Genome packaging for viruses with segmented genomes is often a complex problem. This is
particularly true for influenza viruses and other orthomyxoviruses, whose genome consists of …