Acute viral pneumonia is an important cause of acute lung injury (ALI), although not enough
is known about the exact incidence of viral infection in ALI. Polymerase chain reaction …

Severe acute respiratory syndrome (SARS)–coronavirus (CoV) produces a devastating
primary viral pneumonia with diffuse alveolar damage and a marked increase in circulating …

In 2012, a novel betacoronavirus, designated Middle East respiratory syndrome coronavirus
or MERS-CoV and associated with severe respiratory disease in humans, emerged in the …

Since April 2012, there have been 17 laboratory-confirmed human cases of respiratory
disease associated with newly recognized human betacoronavirus lineage C virus EMC …

The severe acute respiratory syndrome coronavirus accessory protein ORF6 antagonizes
interferon signaling by blocking karyopherin-mediated nuclear import processes. Viral …

Progress in the development of antivirals for non‐influenza respiratory viruses has been
slow with the result that many unmet medical needs and few approved agents currently …

Highlights•Efficient responses to viral threats require a integrated multidisciplinary
approach.•Several relatively newly formed initiatives focus on effective response …

Viral diseases are important threats to public health worldwide. With the number of emerging
viral diseases increasing the last decades, there is a growing need for appropriate animal …

Infection of conventional mice with a mouse adapted (MA15) severe acute respiratory
syndrome (SARS) coronavirus (CoV) reproduces many aspects of human SARS such as …

Coronaviruses (CoVs) are a vast and important group of large RNA viruses that possess
unique molecular mechanisms of transcription and recombination, providing diverse models …