B7-H4 enhances oncogenicity and inhibits apoptosis in pancreatic cancer cells
Y Qian, B Hong, L Shen, Z Wu, H Yao, L Zhang - Cell and tissue research, 2013 - Springer
B7-H4 is expressed in a variety of tumor cells and functions as a negative regulator of T
cells. However, clarification is needed as to whether B7-H4 mediates tumorigenesis through …
cells. However, clarification is needed as to whether B7-H4 mediates tumorigenesis through …
EGFR inhibitors exacerbate differentiation and cell cycle arrest induced by retinoic acid and vitamin D3 in acute myeloid leukemia cells
E Lainey, A Wolfromm, AQ Sukkurwala, JB Micol… - Cell Cycle, 2013 - Taylor & Francis
By means of an unbiased, automated fluorescence microscopy-based screen, we identified
the epidermal growth factor receptor (EGFR) inhibitors erlotinib and gefitinib as potent …
the epidermal growth factor receptor (EGFR) inhibitors erlotinib and gefitinib as potent …
Retinoic acid-elicited RARα/RXRα signaling attenuates Aβ production by directly inhibiting γ-secretase-mediated cleavage of amyloid precursor protein
A Kapoor, BJ Wang, WM Hsu, MY Chang… - ACS chemical …, 2013 - ACS Publications
Retinoic acid (RA)-elicited signaling has been shown to play critical roles in development,
organogenesis, and the immune response. RA regulates expression of Alzheimer's disease …
organogenesis, and the immune response. RA regulates expression of Alzheimer's disease …
6-Formylindolo (3, 2-b) carbazole (FICZ) enhances retinoic acid (RA)-induced differentiation of HL-60 myeloblastic leukemia cells
RP Bunaciu, A Yen - Molecular cancer, 2013 - Springer
Background The aryl hydrocarbon receptor (AhR) ligand 6-Formylindolo (3, 2-b) carbazole
(FICZ) has received increasing attention since its identification as an endogenous AhR …
(FICZ) has received increasing attention since its identification as an endogenous AhR …
Regulation of the osterix (Osx, Sp7) promoter by osterix and its inhibition by parathyroid hormone
R Barbuto, J Mitchell - Journal of Molecular Endocrinology, 2013 - jme.bioscientifica.com
The oxidation and isomerization of 3beta-hydroxy-5-ene steroids into keto-4-ene steroids, a
pivotal step in the synthesis of all hormonal steroids, is catalyzed by several isoforms of …
pivotal step in the synthesis of all hormonal steroids, is catalyzed by several isoforms of …
Mesenchymal stem cells induce granulocytic differentiation of acute promyelocytic leukemic cells via IL-6 and MEK/ERK pathways
F Chen, K Zhou, L Zhang, F Ma, D Chen… - Stem cells and …, 2013 - liebertpub.com
All-trans retinoic acid (ATRA) induces clinical remission in most acute promyelocytic
leukemia (APL) patients by inducing terminal differentiation of APL cells toward mature …
leukemia (APL) patients by inducing terminal differentiation of APL cells toward mature …
[图书][B] Inflammation, oxidative stress, and cancer: dietary approaches for cancer prevention
ANT Kong - 2013 - books.google.com
Increasing scientific evidence suggests that the majority of diseases including cancer are
driven by oxidative stress and inflammation, attributed to environmental factors. These …
driven by oxidative stress and inflammation, attributed to environmental factors. These …
The Src-family kinase inhibitor PP2 rescues inducible differentiation events in emergent retinoic acid-resistant myeloblastic leukemia cells
HA Jensen, LE Styskal, R Tasseff, RP Bunaciu… - PLoS …, 2013 - journals.plos.org
Retinoic acid is an embryonic morphogen and dietary factor that demonstrates
chemotherapeutic efficacy in inducing maturation in leukemia cells. Using HL60 model …
chemotherapeutic efficacy in inducing maturation in leukemia cells. Using HL60 model …
Immunolocalization of retinoic acid receptor-alpha,-beta, and-gamma, in bovine and canine sperm
VR Kasimanickam, RK Kasimanickam, HA Rogers - Theriogenology, 2013 - Elsevier
Retinoic acid is an important regulator of cellular proliferation and differentiation. The action
of retinoic acid is mediated by retinoic acid receptors (RARs) and the retinoid X receptors …
of retinoic acid is mediated by retinoic acid receptors (RARs) and the retinoid X receptors …
Phosphorylation of serine 323 of ASB2α is pivotal for the targeting of filamin A to degradation
R Zakaria, I Lamsoul, S Uttenweiler-Joseph, M Erard… - Cellular …, 2013 - Elsevier
ASB proteins are the specificity subunits of cullin5-RING E3 ubiquitin ligases (CRL5) that
play roles in ubiquitin-mediated protein degradation. However, how their activity is regulated …
play roles in ubiquitin-mediated protein degradation. However, how their activity is regulated …