Role of microRNAs in Semaphorin function and neural circuit formation

ML Baudet, A Bellon, CE Holt - Seminars in cell & developmental biology, 2013 - Elsevier
Since the discovery of the first microRNA (miRNA) almost 20 years ago, insight into their
functional role has gradually been accumulating. This class of non-coding RNAs has …

Argonaute-3 activates the let-7a passenger strand microRNA

J Winter, S Diederichs - RNA biology, 2013 - Taylor & Francis
MicroRNA duplices are separated into a guide and a passenger strand. By convention, the
guide represents the active microRNA while the passenger is supposedly degraded …

Developing gene knockdown-replacement therapies for spinocerebellar ataxia type 7

H Curtis, H Curtis - 2013 - ora.ox.ac.uk
For many dominant diseases, conventional treatment options are limited. This makes them
attractive candidates for gene therapy, which may be directed to specifically silence a …