Dietary (poly) phenolics in human health: structures, bioavailability, and evidence of protective effects against chronic diseases

D Del Rio, A Rodriguez-Mateos… - Antioxidants & redox …, 2013 - liebertpub.com
Human intervention trials have provided evidence for protective effects of various (poly)
phenol-rich foods against chronic disease, including cardiovascular disease …

[HTML][HTML] Health benefits of methylxanthines in cacao and chocolate

R Franco, A Oñatibia-Astibia, E Martínez-Pinilla - Nutrients, 2013 - mdpi.com
One may wonder why methylxanthines are so abundant in beverages used by humans for
centuries, or in cola-drinks that have been heavily consumed since their appearance. It is …

[PDF][PDF] Chocolate/cocoa and human health: a review

R Latif - Neth J Med, 2013 - njmonline.nl
Cocoa contains large concentrations of flavonoids, epicatechin, catechin, and procyanidins.
14 Cocoa has the maximum levels of flavonoids, greater than even tea and wine. 15 Dark …

Effects of chocolate on cognitive function and mood: a systematic review

A Scholey, L Owen - Nutrition reviews, 2013 - academic.oup.com
A systematic review was conducted to evaluate whether chocolate or its constituents were
capable of influencing cognitive function and/or mood. Studies investigating potentially …

Dietary quercetin attenuates oxidant-induced endothelial dysfunction and atherosclerosis in apolipoprotein E knockout mice fed a high-fat diet: a critical role for heme …

Y Shen, NC Ward, JM Hodgson, IB Puddey… - Free Radical Biology …, 2013 - Elsevier
Several lines of evidence indicate that quercetin, a polyphenol derived in the diet from fruit
and vegetables, contributes to cardiovascular health. We aimed to investigate the effects of …

[HTML][HTML] Effect of cocoa and theobromine consumption on serum HDL-cholesterol concentrations: a randomized controlled trial

N Neufingerl, YEMP Zebregs, EAH Schuring… - The American journal of …, 2013 - Elsevier
Background: Evidence from clinical studies has suggested that cocoa may increase high-
density lipoprotein (HDL)–cholesterol concentrations. However, it is unclear whether this …

Cardioprotective effects of cocoa: Clinical evidence from randomized clinical intervention trials in humans

S Arranz, P Valderas‐Martinez… - Molecular Nutrition & …, 2013 - Wiley Online Library
Cocoa is an important source of polyphenols, which comprise 12–18% of its total dry weight.
The major phenolic compounds in cocoa and cocoa products are mainly flavonoids such as …

Cocoa polyphenols: Can we consider cocoa and chocolate as potential functional food?

D Ackar, K Valek Lendić, M Valek, D Šubarić… - Journal of …, 2013 - Wiley Online Library
Chocolate has been consumed as confection, aphrodisiac, and folk medicine for many years
before science proved its potential health benefiting effects. Main compounds of cocoa and …

(–)‐Epicatechin reduces blood pressure and improves vasorelaxation in spontaneously hypertensive rats by NO‐mediated mechanism

M Galleano, I Bernatova, A Puzserova, P Balis… - IUBMB …, 2013 - Wiley Online Library
Studies in humans have found consumption of certain flavanoid‐containing foods to be
associated with improvement in endothelial function and with reduction of blood pressure …

Cocoa consumption reduces NF-κB activation in peripheral blood mononuclear cells in humans

M Vázquez-Agell, M Urpi-Sarda, E Sacanella… - Nutrition, metabolism …, 2013 - Elsevier
BACKGROUND AND AIMS: Epidemiological studies have demonstrated an association
between high-polyphenol intake and reduced incidence of atherosclerosis. The healthy …