Objective Attention‐deficit/hyperactivity disorder (ADHD) is an etiologically complex heterogeneous behavioral disorder. Several studies have reported that ADHD subjects are …
Recent advances in high-throughput sequencing technologies make it increasingly more efficient to sequence large cohorts for many complex traits. We discuss here a class of …
Exposure to stressors results in a spectrum of autonomic, endocrine, and behavioral responses. A key pathway in this response to stress is the hypothalamic–pituitary–adrenal …
Advances in genome sequencing are providing unprecedented resolution of rare and private variants. However, methods which assess the effect of these variants have relied …
MS Dutra, SR Béla, AL Peixoto-Rangel… - The Journal of …, 2013 - academic.oup.com
Retinochoroiditis manifests in patients infected with Toxoplasma gondii. Here, we assessed 30 sibships and 89 parent/case trios of presumed ocular toxoplasmosis (POT) to evaluate …
JJ McElroy, CE Gutman, CM Shaffer, TD Busch… - Human genetics, 2013 - Springer
Preterm birth (PTB) is a major global public health concern. However, little is known about the pathophysiology of spontaneous idiopathic PTB. We tested the hypothesis that rare …
J Kim, KJ Stirling, ME Cooper, M Ascoli… - BMC medical …, 2013 - Springer
Background Preterm birth (PTB) is a complex disorder associated with significant neonatal mortality and morbidity and long-term adverse health consequences. Multiple lines of …
S Sampath, S Bhat, S Gupta, A O'Connor, AB West… - PloS one, 2013 - journals.plos.org
Multiple lines of genetic evidence suggest a role for CNTNAP2 in autism. To assess its population impact we studied 2148 common single nucleotide polymorphisms (SNPs) using …
C Seneviratne, J Franklin, K Beckett, JZ Ma… - Human genetics, 2013 - Springer
On the basis of the converging evidence showing regulation of drinking behavior by 5-HT 3AB receptors and the serotonin transporter, we hypothesized that the interactive effects of …