Meta‐analysis of association between obsessive‐compulsive disorder and the 3′ region of neuronal glutamate transporter gene SLC1A1

SE Stewart, C Mayerfeld, PD Arnold… - American Journal of …, 2013 - Wiley Online Library
The neuronal glutamate transporter gene SLC1A1 is a candidate gene for obsessive‐
compulsive disorder (OCD) based on linkage studies and convergent evidence implicating …

Association between obesity‐related gene FTO and ADHD

Z Choudhry, SM Sengupta, N Grizenko, GA Thakur… - …, 2013 - Wiley Online Library
Objective Attention‐deficit/hyperactivity disorder (ADHD) is an etiologically complex
heterogeneous behavioral disorder. Several studies have reported that ADHD subjects are …

[HTML][HTML] Family-based association tests for sequence data, and comparisons with population-based association tests

I Ionita-Laza, S Lee, V Makarov, JD Buxbaum… - European Journal of …, 2013 - nature.com
Recent advances in high-throughput sequencing technologies make it increasingly more
efficient to sequence large cohorts for many complex traits. We discuss here a class of …

Genetic evidence for the association of the hypothalamic–pituitary–adrenal (HPA) axis with ADHD and methylphenidate treatment response

MÈ Fortier, SM Sengupta, N Grizenko… - Neuromolecular …, 2013 - Springer
Exposure to stressors results in a spectrum of autonomic, endocrine, and behavioral
responses. A key pathway in this response to stress is the hypothalamic–pituitary–adrenal …

[HTML][HTML] Detection and impact of rare regulatory variants in human disease

X Li, SB Montgomery - Frontiers in genetics, 2013 - frontiersin.org
Advances in genome sequencing are providing unprecedented resolution of rare and
private variants. However, methods which assess the effect of these variants have relied …

Association of a NOD2 gene polymorphism and T-helper 17 cells with presumed ocular toxoplasmosis

MS Dutra, SR Béla, AL Peixoto-Rangel… - The Journal of …, 2013 - academic.oup.com
Retinochoroiditis manifests in patients infected with Toxoplasma gondii. Here, we assessed
30 sibships and 89 parent/case trios of presumed ocular toxoplasmosis (POT) to evaluate …

Maternal coding variants in complement receptor 1 and spontaneous idiopathic preterm birth

JJ McElroy, CE Gutman, CM Shaffer, TD Busch… - Human genetics, 2013 - Springer
Preterm birth (PTB) is a major global public health concern. However, little is known about
the pathophysiology of spontaneous idiopathic PTB. We tested the hypothesis that rare …

[HTML][HTML] Sequence variants in oxytocin pathway genes and preterm birth: a candidate gene association study

J Kim, KJ Stirling, ME Cooper, M Ascoli… - BMC medical …, 2013 - Springer
Background Preterm birth (PTB) is a complex disorder associated with significant neonatal
mortality and morbidity and long-term adverse health consequences. Multiple lines of …

[HTML][HTML] Defining the Contribution of CNTNAP2 to Autism Susceptibility

S Sampath, S Bhat, S Gupta, A O'Connor, AB West… - PloS one, 2013 - journals.plos.org
Multiple lines of genetic evidence suggest a role for CNTNAP2 in autism. To assess its
population impact we studied 2148 common single nucleotide polymorphisms (SNPs) using …

Association, interaction, and replication analysis of genes encoding serotonin transporter and 5-HT3 receptor subunits A and B in alcohol dependence

C Seneviratne, J Franklin, K Beckett, JZ Ma… - Human genetics, 2013 - Springer
On the basis of the converging evidence showing regulation of drinking behavior by 5-HT
3AB receptors and the serotonin transporter, we hypothesized that the interactive effects of …