Impact of obesity on cardiovascular health

M Chrostowska, A Szyndler, M Hoffmann… - Best practice & research …, 2013 - Elsevier
This review examines the impact of obesity on cardiovascular health. We will review first,
relationship between obesity and hypertension. Second, we will describe obesity-related …

Energy dissipation in brown adipose tissue: from mice to men

MJ Vosselman, WD van Marken Lichtenbelt… - Molecular and cellular …, 2013 - Elsevier
In rodents, brown adipose tissue (BAT) is a metabolic organ that produces heat in response
to cold and dietary intake through mitochondrial uncoupling. For long time, BAT was …

The identification of 14 new genes for meat quality traits in chicken using a genome-wide association study

Y Sun, G Zhao, R Liu, M Zheng, Y Hu, D Wu, L Zhang… - BMC genomics, 2013 - Springer
Background Meat quality is an important economic trait in chickens. To identify loci and
genes associated with meat quality traits, we conducted a genome-wide association study …

NH2-Terminal Pro–Brain Natriuretic Peptide and Risk of Diabetes

M Lazo, JH Young, FL Brancati, J Coresh, S Whelton… - Diabetes, 2013 - Am Diabetes Assoc
Brain natriuretic peptide (BNP) has an established role in cardiovascular disease (CVD).
However, recent animal studies suggest direct metabolic effects of BNP. To determine the …

Beneficial and adverse effects of testosterone on the cardiovascular system in men

JB Ruige, DM Ouwens… - The Journal of Clinical …, 2013 - academic.oup.com
Context: The widespread use of T therapy, particularly in aging males, necessitates
knowledge of the relationship between T and the cardiovascular system. Evidence …

The role of natriuretic peptides as biomarkers for guiding the management of chronic heart failure

SR Motiwala, JL Januzzi Jr - Clinical Pharmacology & …, 2013 - Wiley Online Library
The current standard treatment of chronic heart failure (HF) is based on clinical judgment,
with the goal of achieving the maximally tolerated therapeutic program. The complexity of …

The atrial natriuretic peptide genetic variant rs5068 is associated with a favorable cardiometabolic phenotype in a Mediterranean population

V Cannone, AB Cefalu', D Noto, CG Scott… - Diabetes …, 2013 - Am Diabetes Assoc
OBJECTIVE We hypothesized that the minor allele of the atrial natriuretic peptide (ANP)
genetic variant rs5068 is associated with a favorable cardiometabolic phenotype in a …

Relative atrial natriuretic peptide deficiency and inadequate renin and angiotensin II suppression in obese hypertensive men

CL Asferg, SJ Nielsen, UB Andersen, A Linneberg… - …, 2013 - Am Heart Assoc
Obesity is a strong risk factor for hypertension, but the mechanisms by which obesity leads to
hypertension are incompletely understood. On this background, we assessed dietary …

Pathophysiology-based novel pharmacotherapy for heart failure with preserved ejection fraction

DM Konstantinou, YS Chatzizisis… - Pharmacology & …, 2013 - Elsevier
Heart failure has become increasingly prevalent and poses a significant socioeconomic
burden in the developed world. Approximately half of heart failure patients have preserved …

Insulin status and vascular responses to weight loss in obesity

SJ Bigornia, MG Farb, S Tiwari, S Karki… - Journal of the American …, 2013 - jacc.org
Objectives: The aim of this study was to determine whether the effects of weight loss on
arterial function are differentially modified by insulin status. Background: Clinical studies …