[HTML][HTML] Crosstalk between diabetes and brain: glucagon-like peptide-1 mimetics as a promising therapy against neurodegeneration
According to World Health Organization estimates, type 2 diabetes (T2D) is an epidemic
(particularly in under development countries) and a socio-economic challenge. This is even …
(particularly in under development countries) and a socio-economic challenge. This is even …
Pathological parainflammation and endoplasmic reticulum stress in depression: potential translational targets through the CNS insulin, klotho and PPAR-γ systems
Major depression and bipolar disorder are heterogeneous conditions in which there can be
dysregulation of (1) the stress system response,(2) its capacity for counterregulation after …
dysregulation of (1) the stress system response,(2) its capacity for counterregulation after …
N‐docosahexaenoylethanolamine is a potent neurogenic factor for neural stem cell differentiation
Docosahexaenoic acid (DHA) has been shown to promote neuronal differentiation of neural
stem cells (NSC s) in vivo and in vitro. Previously, we found that N …
stem cells (NSC s) in vivo and in vitro. Previously, we found that N …
Perfluorooctane sulfonate induces neuronal and oligodendrocytic differentiation in neural stem cells and alters the expression of PPARγ in vitro and in vivo
WNW Ibrahim, R Tofighi, N Onishchenko… - Toxicology and applied …, 2013 - Elsevier
Perfluorinated compounds are ubiquitous chemicals of major concern for their potential
adverse effects on the human population. We have used primary rat embryonic neural stem …
adverse effects on the human population. We have used primary rat embryonic neural stem …
The role of nuclear receptors in controlling the fine balance between proliferation and differentiation of neural stem cells
A Stergiopoulos, PK Politis - Archives of Biochemistry and Biophysics, 2013 - Elsevier
In the central nervous system (CNS) of vertebrates a large variety of cell types are specified
from a pool of highly plastic neural stem/progenitor cells (NSCs) via a combined action of …
from a pool of highly plastic neural stem/progenitor cells (NSCs) via a combined action of …
Role of Peroxisome Proliferator‐Activated Receptor β/δ and B‐Cell Lymphoma‐6 in Regulation of Genes Involved in Metastasis and Migration in Pancreatic Cancer …
JD Coleman, JT Thompson, RW Smith III… - PPAR …, 2013 - Wiley Online Library
PPARβ/δ is a ligand‐activated transcription factor that regulates various cellular functions
via induction of target genes directly or in concert with its associated transcriptional …
via induction of target genes directly or in concert with its associated transcriptional …
Relationships between dietary macronutrients and adult neurogenesis in the regulation of energy metabolism
MA Yon, SL Mauger, LC Pickavance - British journal of nutrition, 2013 - cambridge.org
Of the environmental factors which have an impact on body weight, nutrients are most
influential. Within normal limits, hypothalamic and related neuronal populations correct …
influential. Within normal limits, hypothalamic and related neuronal populations correct …
PPARs: a potential target for a disease-modifying strategy in stroke
T Ouk, C Potey, S Gautier, M Bastide… - Current drug …, 2013 - ingentaconnect.com
Stroke is one of the major causes of mortality and disability in adults in industrialized
countries. Despite numerous preclinical studies and clinical trials in the field of cerebral …
countries. Despite numerous preclinical studies and clinical trials in the field of cerebral …
PPARγ 在神经系统中能够促进IRS-4 基因表达
章红妍， 蒙思颖， 林利芳， 吴巧琪， 周日阳， 王雪敏 - 南方医科大学学报, 2013 - cqvip.com
目的探讨过氧化物酶体增殖物激活受体γ (PPARγ) 对脑内胰岛素受体底物-4 (IRS-4)
基因表达的影响. 方法体外实验采用原代培养1 周的大鼠皮层神经元, 用10μmol/LPPARγ …
基因表达的影响. 方法体外实验采用原代培养1 周的大鼠皮层神经元, 用10μmol/LPPARγ …