Background Any form of screening aims to reduce disease‐specific and overall mortality,
and to improve a person's future quality of life. Screening for prostate cancer has generated …

Autopsy studies have shown the presence of a large reservoir of latent prostate cancers in
adult men. Serum PSA testing of asymptomatic men leads to the detection of a proportion of …

BACKGROUND: Overdiagnosis and subsequent overtreatment are important side effects of
screening for, and early detection of, prostate cancer (PCa). Active surveillance (AS) is of …

Increasing evidence suggests that prostate cancer is overdiagnosed and overtreated, and
prognostic biomarkers would aid in treatment selection. To define prognostic biomarkers for …

Focal therapy is an emerging treatment modality for localised prostate cancer that aims to
reduce the morbidity seen with radical therapy, while maintaining cancer control. Focal …

Background: Screening for prostate cancer (PC) may save lives, but overdiagnosis and
overtreatment are serious drawbacks. We aimed to determine men's preferences for PC …

Background. As prostate cancer (PC) mortality reduction results are not unequivocal, a
special emphasis has to be put on other aspects of the prostate-specific antigen (PSA) …

Background: The effectiveness of prostate-specific antigen (PSA) for population screening
has presented controversial results in large trials and prior reviews. We investigated the …

Background There is scant data regarding disease presentation and treatment response
among black men living in Africa. In this study we evaluate disease presentation and early …

Prostate cancer (PCa) is the most frequently diagnosed type of cancer in developed
countries. The decisive method of diagnosis is based on the results of biopsies …