Morin reduces hepatic inflammation-associated lipid accumulation in high fructose-fed rats via inhibiting sphingosine kinase 1/sphingosine 1-phosphate signaling …

X Wang, DM Zhang, TT Gu, XQ Ding, CY Fan… - Biochemical …, 2013 - Elsevier
SphK1/S1P signaling pathway is involved in the development of hepatic inflammation and
injury. But its role in high fructose-induced NAFLD has not yet been reported. The aim of this …

Fructose during pregnancy affects maternal and fetal leptin signaling

L Rodríguez, MI Panadero, N Roglans, P Otero… - The Journal of …, 2013 - Elsevier
Fructose intake from added sugars correlates with the epidemic rise in obesity, metabolic
syndrome and cardiovascular diseases. Fructose intake also causes features of metabolic …

Oxymatrine attenuates hepatic steatosis in non-alcoholic fatty liver disease rats fed with high fructose diet through inhibition of sterol regulatory element binding …

L Shi, L Shi, G Song, H Zhang, Z Hu, C Wang… - European journal of …, 2013 - Elsevier
The aim of this study was to examine the therapeutic effect of oxymatrine, a monomer
isolated from the medicinal plant Sophora flavescens Ait, on the hepatic lipid metabolism in …

Tissue-specific regulation of inflammation by macrophage migration inhibitory factor and glucocorticoids in fructose-fed Wistar rats

N Veličković, A Djordjevic, A Vasiljević… - British journal of …, 2013 - cambridge.org
High fructose consumption is commonly associated with insulin resistance, disturbed
glucose homeostasis and low-grade inflammation. Increased glucocorticoid production …

Oleanolic acid diminishes liquid fructose‐induced fatty liver in rats: role of modulation of hepatic sterol regulatory element‐binding protein‐1c‐mediated expression of …

C Liu, Y Li, G Zuo, W Xu, H Gao, Y Yang… - Evidence‐Based …, 2013 - Wiley Online Library
Oleanolic acid (OA), contained in more than 1620 plants and as an aglycone precursor for
naturally occurred and synthesized triterpenoid saponins, is used in China for liver disorders …

High dietary salt decreases antioxidant defenses in the liver of fructose-fed insulin-resistant rats

WC Dornas, WG de Lima, RC dos Santos… - The Journal of …, 2013 - Elsevier
In this study we investigated the hypothesis that a high-salt diet to hyperinsulinemic rats
might impair antioxidant defense owing to its involvement in the activation of sodium …

Plasma lipid levels and body weight altered by intrauterine growth restriction and postnatal fructose diet in adult rats

E Malo, M Saukko, M Santaniemi, M Hietaniemi… - Pediatric …, 2013 - nature.com
Background: Intrauterine growth restriction (IUGR) is known to affect the risk of adult
diseases. Consumption of lipogenic fructose is increasing, and it is used as an enhancer of …

Monascin improves diabetes and dyslipidemia by regulating PPARγ and inhibiting lipogenesis in fructose-rich diet-induced C57BL/6 mice

BH Lee, WH Hsu, T Huang, YY Chang, YW Hsu… - Food & function, 2013 - pubs.rsc.org
Monascin (MS) is a yellow compound isolated from Monascus-fermented products that has
pancreatic protective, anti-inflammatory, anti-oxidative, and hypolipidemic activity. We …

Enhanced prereceptor glucocorticoid metabolism and lipogenesis impair insulin signaling in the liver of fructose-fed rats

A Vasiljević, N Veličković, B Bursać, A Djordjevic… - The Journal of …, 2013 - Elsevier
Overconsumption of fructose, as a highly lipogenic sugar, may profoundly affect hepatic
metabolism and has been associated with many components of the metabolic syndrome …

[引用][C] 非酒精性脂肪肝的发病机制及其饮食干预

周峰, 华春, 李建梅 - 中国老年学杂志, 2013