Cellular and population plasticity of helper CD4+ T cell responses

G Magombedze, PBJ Reddy, S Eda… - Frontiers in …, 2013 - frontiersin.org
Vertebrates are constantly exposed to pathogens, and the adaptive immunity has most likely
evolved to control and clear such infectious agents. CD4+ T cells are the major players in …

Placebo‐controlled randomized clinical trial on the immunomodulating activities of low‐and high‐dose bromelain after oral administration–new evidence on the …

S Müller, R März, M Schmolz, B Drewelow… - Phytotherapy …, 2013 - Wiley Online Library
Bromelain has been used for treatment of inflammatory diseases for decades. However, the
exact mechanism of action remains poorly understood. While in vitro investigations have …

A virtual culture of CD4+ T lymphocytes

L Mendoza - Bulletin of mathematical biology, 2013 - Springer
The CD4+ T cell lineages Th1, Th2, Th17, and Treg, are mammalian cell types that
differentiate from the common precursor naive CD4+ T cell. While there is a wealth of …

[HTML][HTML] The onset of type 2 diabetes: proposal for a multi-scale model

F Castiglione, P Tieri, A De Graaf… - JMIR research …, 2013 - researchprotocols.org
Background: Type 2 diabetes mellitus (T2D) is a common age-related disease, and is a
major health concern, particularly in developed countries where the population is aging …

Agent-based modeling in translational systems biology

S Christley, G An - … systems and computational biology approaches to …, 2013 - Springer
Agent-based modeling is an object-oriented, discrete event, population-focused method for
the computational representation of dynamic systems. Agent-based models (ABMs) treat …

Agent-based modeling approaches to multi-scale systems biology: An example agent-based model of acute pulmonary inflammation

G An, M Wandling, S Christley - Systems biology: Integrative biology and …, 2013 - Springer
Implicit in systems biology is the concept that the whole is greater than the sum of its parts.
Agent-based modeling, an object-oriented, discrete event, population-based computational …

Modeling and Simulating Influenza with Immune-B

S Zou, X Yang, Z Du, Y Jin - 2013 10th Web Information System …, 2013 - ieeexplore.ieee.org
Influenza virus causes an acute, mostly self-limited, infection of the upper respiratory tract.
Several aspects of influenza infections are still unresolved. Most of these unresolved …

Computational biology modeling across different scales

F Castiglione, F Pappalardo - Special Session on Modelling and …, 2013 - scitepress.org
One of the most formidable challenges in modern biology is to get a unified view of the
various mechanisms governing the behavior and of the causal relationships among different …

Modeling CAS

MA Niazi, A Hussain, MA Niazi, A Hussain - Cognitive Agent-based …, 2013 - Springer
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