External influence of early childhood establishment of gut microbiota and subsequent health implications

PM Munyaka, E Khafipour, JE Ghia - Frontiers in pediatrics, 2014 - frontiersin.org
Postnatal maturation of immune regulation is largely driven by exposure to microbes. The
gastrointestinal tract is the largest source of microbial exposure, as the human gut …

Microbial 'old friends', immunoregulation and socioeconomic status

GAW Rook, CL Raison, CA Lowry - Clinical & Experimental …, 2014 - academic.oup.com
The immune system evolved to require input from at least three sources that we collectively
term the 'old friends':(i) the commensal microbiotas transmitted by mothers and other family …

Lung microbiota promotes tolerance to allergens in neonates via PD-L1

ES Gollwitzer, S Saglani, A Trompette, K Yadava… - Nature medicine, 2014 - nature.com
Epidemiological data point toward a critical period in early life during which environmental
cues can set an individual on a trajectory toward respiratory health or disease,,,,,,,. The …

[HTML][HTML] Lactobacilli and bifidobacteria in human breast milk: influence of antibiotherapy and other host and clinical factors

A Soto, V Martín, E Jiménez, I Mader… - Journal of pediatric …, 2014 - journals.lww.com
Objective: The objective of this work was to study the lactobacilli and bifidobacteria
population in human milk of healthy women, and to investigate the influence that several …

[PDF][PDF] Antibiotics in fetal and early life and subsequent childhood asthma: nationwide population based study with sibling analysis

AK Örtqvist, C Lundholm, H Kieler, JF Ludvigsson… - Bmj, 2014 - bmj.com
Objective To investigate the association between exposure to antibiotics in fetal and early
life and asthma in childhood, with adjustment for confounding factors. Design Nationwide …

Maternal propensity for infections and risk of childhood asthma: a registry-based cohort study

J Stokholm, A Sevelsted, K Bønnelykke… - The Lancet Respiratory …, 2014 - thelancet.com
Background Maternal use of antibiotics during pregnancy has been associated with the
development of asthmatic disorders in the offspring. The human microbiome has been …

[HTML][HTML] Antibiotic use during pregnancy alters the commensal vaginal microbiota

J Stokholm, S Schjørring, CE Eskildsen… - Clinical Microbiology …, 2014 - Elsevier
Antibiotics may induce alterations in the commensal microbiota of the birth canal in pregnant
women. Therefore, we studied the effect of antibiotic administration during pregnancy on …

Microbiota, immunoregulatory old friends and psychiatric disorders

GAW Rook, CL Raison, CA Lowry - … : The microbiota-gut-brain axis in …, 2014 - Springer
Regulation of the immune system is an important function of the gut microbiota. Increasing
evidence suggests that modern living conditions cause the gut microbiota to deviate from the …

The evolution of the hygiene hypothesis: the role of early-life exposures to viruses and microbes and their relationship to asthma and allergic diseases

D Daley - Current opinion in allergy and clinical immunology, 2014 - journals.lww.com
Susceptibility to asthma and allergic diseases is complex and involves genetic variants and
environmental exposures (bacteria, viruses, smoking, and pet ownership), alteration of our …

Probiotics for human lactational mastitis

L Fernández, R Arroyo, I Espinosa… - Beneficial …, 2014 - wageningenacademic.com
The use of culture-dependent and-independent techniques to study the human milk
microbiota and microbiome has revealed a complex ecosystem with a much greater diversity …