Purinergic signaling and blood vessels in health and disease

G Burnstock, V Ralevic - Pharmacological reviews, 2014 - ASPET
Purinergic signaling plays important roles in control of vascular tone and remodeling. There
is dual control of vascular tone by ATP released as a cotransmitter with noradrenaline from …

The challenge of translating ischemic conditioning from animal models to humans: the role of comorbidities

K McCafferty, S Forbes… - Disease models & …, 2014 - journals.biologists.com
Following a period of ischemia (local restriction of blood supply to a tissue), the restoration of
blood supply to the affected area causes significant tissue damage. This is known as …

Role of Phospholipase C in Cardioprotection During Oxidative Stress

PS Tappia, NS Dhalla - Phospholipases in Health and Disease, 2014 - Springer
It is well known that myocardial ischemia–reperfusion (IR) results in contractile dysfunction
due to Ca 2+-handling abnormalities in cardiomyocytes; these defects are primarily due to …