Vaccines are one of the most effective interventions to improve public health, however, the
generation of highly effective vaccines for many diseases has remained difficult. Three …

Ribonucleoprotein (RNP) granules are important posttranscriptional regulators of
messenger RNA (mRNA) fate. Several types of RNP granules specifically regulate gene …

The prodigious rate at which malaria parasites proliferate during asexual blood-stage
replication, midgut sporozoite production, and intrahepatic development creates a …

Background Following fertilization, the early proteomes of metazoans are defined by the
translation of stored but repressed transcripts; further embryonic development relies on de …

Malaria parasites scavenge nutrients from their host but also harbour enzymatic pathways
for de novo macromolecule synthesis. One such pathway is apicoplast‐targeted type II fatty …

P lasmodium sporozoites are transmitted by mosquitoes and first infect hepatocytes of their
mammalian host, wherein they develop as liver stages, surrounded by the parasitophorous …

Malaria plagues one out of every 30 humans and contributes to almost a million deaths, and
the problem could worsen. Our current therapeutic options are compromised by emerging …

Highlights•Gene expression mechanisms downstream of transcriptional initiation in
Apicomplexa are highlighted.•Deep RNA sequencing has revealed a wealth of RNA …