The skin protects the body from unwanted influences from the environment as well as
excessive water loss. The barrier function of the skin is located in the stratum corneum (SC) …

Psoriasis is a chronic, inflammatory, immune-mediated skin condition with a prevalence of 0–
11.8% across the world. It is associated with a number of cardiovascular, metabolic, and …

Background We analysed incidence, predictors, histological features and specific treatment
options of anti-tumour necrosis factor α (TNF-α) antibody-induced psoriasiform skin lesions …

To explore the contribution of functional coding variants to psoriasis, we analyzed
nonsynonymous single-nucleotide variants (SNVs) across the genome by exome …

We performed a genome-wide association study for primary open-angle glaucoma (POAG)
in 1,007 cases with high-pressure glaucoma (HPG) and 1,009 controls from southern China …

Background Quantitative traits, such as disease resistance, are most often controlled by a
set of genes involving a complex array of regulation. The dissection of genetic basis of …

Candidaemia is the fourth most common cause of bloodstream infection, with a high
mortality rate of up to 40%. Identification of host genetic factors that confer susceptibility to …

In a previous large-scale exome sequencing analysis for psoriasis, we discovered seven
common and low-frequency missense variants within six genes with genome-wide …

Psoriasis vulgaris and psoriatic arthritis are interrelated disorders with an important genetic
component. While linkage studies have identified several candidate loci and genes, only …

Spondyloarthritis (SpA) represents a group of inflammatory rheumatic diseases that cluster
within families and possess overlapping clinical features. The pathogenesis of SpA …