Brain networks in schizophrenia

MP Van Den Heuvel, A Fornito - Neuropsychology review, 2014 - Springer
Schizophrenia—a severe psychiatric condition characterized by hallucinations, delusions,
loss of initiative and cognitive function—is hypothesized to result from abnormal anatomical …

Great expectations: using whole-brain computational connectomics for understanding neuropsychiatric disorders

G Deco, ML Kringelbach - Neuron, 2014 - cell.com
The study of human brain networks with in vivo neuroimaging has given rise to the field of
connectomics, furthered by advances in network science and graph theory informing our …

The frontoparietal control system: a central role in mental health

MW Cole, G Repovš, A Anticevic - The Neuroscientist, 2014 - journals.sagepub.com
Recent findings suggest the existence of a frontoparietal control system consisting of flexible
hubs that regulate distributed systems (eg, visual, limbic, motor) according to current task …

Reviewing the ketamine model for schizophrenia

J Frohlich, JD Van Horn - Journal of psychopharmacology, 2014 - journals.sagepub.com
The observation that antagonists of the N-methyl-D-aspartate receptor (NMDAR), such as
phencyclidine (PCP) and ketamine, transiently induce symptoms of acute schizophrenia had …

A review of structural neuroimaging in schizophrenia: from connectivity to connectomics

AL Wheeler, AN Voineskos - Frontiers in human neuroscience, 2014 - frontiersin.org
In patients with schizophrenia neuroimaging studies have revealed global differences with
some brain regions showing focal abnormalities. Examining neurocircuitry, diffusion …

Changes in the adolescent brain and the pathophysiology of psychotic disorders

MS Keshavan, J Giedd, JYF Lau, DA Lewis… - The Lancet …, 2014 - thelancet.com
Adolescence is a time of extensive neuroanatomical, functional, and chemical
reorganisation of the brain which parallels substantial maturational changes in cognition …

Structural and functional aspects relating to cost and benefit of rich club organization in the human cerebral cortex

G Collin, O Sporns, RCW Mandl… - Cerebral …, 2014 - academic.oup.com
Recent findings have demonstrated that a small set of highly connected brain regions may
play a central role in enabling efficient communication between cortical regions, together …

Structural and functional rich club organization of the brain in children and adults

DS Grayson, S Ray, S Carpenter, S Iyer, TGC Dias… - PloS one, 2014 - journals.plos.org
Recent studies using Magnetic Resonance Imaging (MRI) have proposed that the brain's
white matter is organized as a rich club, whereby the most highly connected regions of the …

Structural connectivity differences in left and right temporal lobe epilepsy

P Besson, V Dinkelacker, R Valabregue, L Thivard… - Neuroimage, 2014 - Elsevier
Our knowledge on temporal lobe epilepsy (TLE) with hippocampal sclerosis has evolved
towards the view that this syndrome affects widespread brain networks. Diffusion weighted …

Impaired rich club connectivity in unaffected siblings of schizophrenia patients

G Collin, RS Kahn, MA De Reus, W Cahn… - Schizophrenia …, 2014 - academic.oup.com
Schizophrenia has been conceptualized as a disorder of brain connectivity. Recent studies
suggest that brain connectivity may be disproportionally impaired among the so-called rich …