Screening for selective inhibitors of xanthine oxidase from Flos Chrysanthemum using ultrafiltration LC–MS combined with enzyme channel blocking

HP Song, H Zhang, Y Fu, H Mo, M Zhang… - … of Chromatography B, 2014 - Elsevier
In this study, a new method based on ultrafiltration liquid chromatography-mass
spectrometry (UF-LC–MS) combined with enzyme channel blocking (ECB) was developed …

Magnetic ligand fishing combination with high-performance liquid chromatography–diode array detector–mass spectrometry to screen and characterize …

X Deng, S Shi, S Li, T Yang - Journal of Chromatography B, 2014 - Elsevier
Abstract Cyclooxygenase-2 (COX-2) inhibitors may be used to efficiently treat inflammation
or cancer diseases. In the present study, we established a new screening assay based on …

Functionalized magnetic nanoparticles coupled with mass spectrometry for screening and identification of cyclooxygenase-1 inhibitors from natural products

Y Zhang, S Shi, X Chen, M Peng - Journal of Chromatography B, 2014 - Elsevier
Abstract Development of simple and effective methods for high-throughput, high-fidelity
screening and identification of cyclooxygenase-1 (COX-1) inhibitors from natural products …

Exploring skyline for both MSE‐based label‐free proteomics and HRMS quantitation of small molecules

S Liu, X Chen, Z Yan, S Qin, J Xu, J Lin, C Yang… - …, 2014 - Wiley Online Library
The MS E (where MS E is low energy (MS) and elevated energy (E) mode of acquisition)
acquisition method commercialized by Waters on its Q‐TOF instruments is regarded as a …