How might ZNF804A variants influence risk for schizophrenia and bipolar disorder? A literature review, synthesis, and bioinformatic analysis
The gene that encodes zinc finger protein 804A (ZNF804A) became a candidate risk gene
for schizophrenia (SZ) after surpassing genome‐wide significance thresholds in replicated …
for schizophrenia (SZ) after surpassing genome‐wide significance thresholds in replicated …
[HTML][HTML] MicroRNA dysregulation, gene networks, and risk for schizophrenia in 22q11. 2 deletion syndrome
The role of microRNAs (miRNAs) in the etiology of schizophrenia is increasingly recognized.
Microdeletions at chromosome 22q11. 2 are recurrent structural variants that impart a high …
Microdeletions at chromosome 22q11. 2 are recurrent structural variants that impart a high …
Heat shock alters the expression of schizophrenia and autism candidate genes in an induced pluripotent stem cell model of the human telencephalon
Schizophrenia (SZ) and autism spectrum disorders (ASD) are highly heritable
neuropsychiatric disorders, although environmental factors, such as maternal immune …
neuropsychiatric disorders, although environmental factors, such as maternal immune …
Variability in working memory performance explained by epistasis vs polygenic scores in the ZNF804A pathway
KK Nicodemus, A Hargreaves, D Morris… - JAMA …, 2014 - jamanetwork.com
Importance We investigated the variation in neuropsychological function explained by risk
alleles at the psychosis susceptibility geneZNF804Aand its interacting partners using single …
alleles at the psychosis susceptibility geneZNF804Aand its interacting partners using single …
A genome-wide association analysis of a broad psychosis phenotype identifies three loci for further investigation
WTCC Consortium… - Biological …, 2014 - Elsevier
Background Genome-wide association studies (GWAS) have identified several loci
associated with schizophrenia and/or bipolar disorder. We performed a GWAS of psychosis …
associated with schizophrenia and/or bipolar disorder. We performed a GWAS of psychosis …
Zinc finger protein 804A (ZNF804A) and verbal deficits in individuals with autism
A Anitha, I Thanseem, K Nakamura, MM Vasu… - Journal of Psychiatry and …, 2014 - jpn.ca
Background: In a genome-wide association study of autism, zinc finger protein 804A
(ZNF804A) single nucleotide polymorphisms (SNPs) were found to be nominally associated …
(ZNF804A) single nucleotide polymorphisms (SNPs) were found to be nominally associated …
Analysis of schizophrenia-related genes and electrophysiological measures reveals ZNF804A association with amplitude of P300b elicited by novel sounds
Several genes have recently been identified as risk factors for schizophrenia (SZ) by
genome-wide association studies (GWAS), including ZNF804A which is thought to function …
genome-wide association studies (GWAS), including ZNF804A which is thought to function …
Evidence of allelic imbalance in the schizophrenia susceptibility gene ZNF804A in human dorsolateral prefrontal cortex
I Guella, A Sequeira, B Rollins, L Morgan… - Schizophrenia …, 2014 - Elsevier
The rs1344706, an intronic SNP within the zinc-finger protein 804A gene (ZNF804A), was
identified as one of the most compelling risk SNPs for schizophrenia (SZ) and bipolar …
identified as one of the most compelling risk SNPs for schizophrenia (SZ) and bipolar …
Sequencing of a patient with balanced chromosome abnormalities and neurodevelopmental disease identifies disruption of multiple high risk loci by structural …
J Blake, A Riddell, S Theiss, AP Gonzalez, B Haase… - PLoS …, 2014 - journals.plos.org
Balanced chromosome abnormalities (BCAs) occur at a high frequency in healthy and
diseased individuals, but cost-efficient strategies to identify BCAs and evaluate whether they …
diseased individuals, but cost-efficient strategies to identify BCAs and evaluate whether they …
Effects of ZNF804A on auditory P300 response in schizophrenia
T O'donoghue, DW Morris, C Fahey, A Da Costa… - Translational …, 2014 - nature.com
The common variant rs1344706 within the zinc-finger protein gene ZNF804A has been
strongly implicated in schizophrenia (SZ) susceptibility by a series of recent genetic …
strongly implicated in schizophrenia (SZ) susceptibility by a series of recent genetic …