Proteins are the major component of the living cell. They play crucial roles in the
maintenance of life, and their dysfunctions are known to cause different pathologies. One of …

The explosion in sequencing technologies has provided us with an instrument to describe
mammalian transcriptomes at unprecedented depths. This has revealed that alternative …

Alternative splicing (AS) is common in higher eukaryotes and plays an important role in
gene posttranscriptional regulation. It has been suggested that AS varies dramatically …

Handedness and brain asymmetry have been linked to neurodevelopmental disorders such
as dyslexia and schizophrenia. The genetic nature of this correlation is not understood …

The relative operating characteristic (ROC) is a popular statistical method to measure the
association between observed and diagnosed presence of a characteristic. The diagnosis of …

Phosphoinositide lipids play a key role in cellular physiology, participating in a wide array of
cellular processes. Consequently, mutation of phosphoinositide‐metabolizing enzymes is …

Abnormal alternative splicing has been associated with cancer. Genome-wide microarrays
can be used to detect differential splicing events. In this study, we have developed …

Gene duplication and alternative splicing are important mechanisms in the production of
genomic novelties. Previous work has shown that a gene's family size and the number of …

Lactoferrin or lactotransferrin is a multifunctional glycoprotein found in blood circulation,
mucosal surfaces, neutrophils, and in various secretory fluids, such as milk, bile, tears, nasal …

Early in development, GABA, an inhibitory neurotransmitter in adults, is excitatory. NKCC1
(SLC12A2) encodes one of two cation chloride cotransporters mediating the conversion of …