Targeted multimodal imaging modalities

SY Lee, SI Jeon, S Jung, IJ Chung, CH Ahn - Advanced drug delivery …, 2014 - Elsevier
Molecular imaging non-invasively visualizes and characterizes the biologic functions and
mechanisms in living organisms at a molecular level. In recent years, advances in imaging …

[HTML][HTML] uPAR-targeted optical imaging contrasts as theranostic agents for tumor margin detection

L Yang, HK Sajja, Z Cao, W Qian, L Bender… - Theranostics, 2014 - ncbi.nlm.nih.gov
Complete removal of tumors by surgery is the most important prognostic factor for cancer
patients with the early stage cancers. The ability to identify invasive tumor edges of the …

Biocompatible Surface-Enhanced Raman Scattering Nanotags for In Vivo Cancer Detection

A Samanta, S Jana, RK Das, YT Chang - Nanomedicine, 2014 - Taylor & Francis
The advancement of surface-enhanced Raman scattering (SERS) is significantly increasing
as an ultra-sensitive sensing technology in biomedical research. In this review, we focus on …

GLP-1R–targeting magnetic nanoparticles for pancreatic islet imaging

P Wang, B Yoo, J Yang, X Zhang, A Ross… - Diabetes, 2014 - Am Diabetes Assoc
Noninvasive assessment of pancreatic β-cell mass would tremendously aid in managing
type 1 diabetes (T1D). Toward this goal, we synthesized an exendin-4 conjugated magnetic …

Sequence‐dependent combination therapy with doxorubicin and a survivin‐specific small interfering RNA nanodrug demonstrates efficacy in models of …

SK Ghosh, MV Yigit, M Uchida, AW Ross… - … journal of cancer, 2014 - Wiley Online Library
The clinical management of cancer reflects a balance between treatment efficacy and
toxicity. While typically, combination therapy improves response rate and time to progression …

Magnetic resonance imaging of glioma with novel APTS-coated superparamagnetic iron oxide nanoparticles

K Li, M Shen, L Zheng, J Zhao, Q Quan, X Shi… - Nanoscale Research …, 2014 - Springer
We report in vitro and in vivo magnetic resonance (MR) imaging of C6 glioma cells with a
novel acetylated 3-aminopropyltrimethoxysilane (APTS)-coated iron oxide nanoparticles (Fe …

Intra-colonic administration of a polymer-bound NIRF probe for improved colorectal cancer detection during colonoscopy

I Kogan-Zviagin, Y Shamay, A Nissan… - Journal of controlled …, 2014 - Elsevier
There is increasing interest in the use of nanoparticle imaging probes for cancer diagnosis.
However, various biological barriers limit the efficient delivery of nanoparticles to tumors …

In vivo NIRF imaging-guided delivery of a novel NGR–VEGI fusion protein for targeting tumor vasculature

W Ma, G Li, J Wang, W Yang, Y Zhang, PS Conti… - Amino Acids, 2014 - Springer
Pathological angiogenesis is crucial in tumor growth, invasion and metastasis. Previous
studies demonstrated that the vascular endothelial growth inhibitor (VEGI), a member of the …

Immunotherapy strategies in multiple myeloma

J Bae, NC Munshi… - Hematology/Oncology …, 2014 - hemonc.theclinics.com
Multiple myeloma (MM) is a B-cell malignancy characterized by the clonal proliferation of
malignant plasma cells in the bone marrow and the development of osteolytic bone lesions …

Ceramic nanoparticles for cancer treatment

A Baeza - Bio‐Ceramics with Clinical Applications, 2014 - Wiley Online Library
In recent years, nanocarriers have offered a promising alternative to conventional therapy in
oncology and have been prepared using a wide range of materials, such as polymers, lipids …