Neuroprotective properties of peroxisome proliferator-activated receptor alpha (PPARα) and its lipid ligands

M Fidaleo, F Fanelli, M Paola Ceru… - Current medicinal …, 2014 - ingentaconnect.com
Signalling lipids are known to control a wide array of cellular processes, including cell
proliferation, apoptosis, migration, and energy metabolism. Fatty acids and their derivatives …

[HTML][HTML] PPAR-γ agonist GW1929 but not antagonist GW9662 reduces TBBPA-induced neurotoxicity in primary neocortical cells

AK Wojtowicz, KA Szychowski, M Kajta - Neurotoxicity Research, 2014 - Springer
Abstract Tetrabromobisphenol A (2, 2-bis (4-hydroxy-3, 5-dibromophenyl) propane; TBBPA)
is a widely used brominated flame retardant. TBBPA induces neuronal damage, but the …

[HTML][HTML] Anti-kindling effect of bezafibrate, a peroxisome proliferator-activated receptors alpha agonist, in pentylenetetrazole induced kindling seizure model

L Saha, S Bhandari, A Bhatia, D Banerjee… - Journal of Epilepsy …, 2014 - ncbi.nlm.nih.gov
Background and Purpose: Studies in the animals suggested that Peroxisome proliferators
activated receptors (PPARs) may be involved in seizure control and selective agonists of …

Changes in endocannabinoid and N-acylethanolamine levels in rat brain structures following cocaine self-administration and extinction training

B Bystrowska, I Smaga, M Frankowska… - Progress in Neuro …, 2014 - Elsevier
Preclinical investigations have demonstrated that drugs of abuse alter the levels of lipid-
based signalling molecules, including endocannabinoids (eCBs) and N-acylethanolamines …

Apoptotic and neurotoxic actions of 4-para-nonylphenol are accompanied by activation of retinoid X receptor and impairment of classical estrogen receptor signaling

E Litwa, J Rzemieniec, A Wnuk, W Lason… - The Journal of steroid …, 2014 - Elsevier
para-Nonylphenol (NP) is a non-ionic surfactant that has widespread and uncontrolled
distribution in the environment. Little is known, however, about its actions on neuronal cells …

[HTML][HTML] Recovery of brain biomarkers following peroxisome proliferator-activated receptor agonist neuroprotective treatment before ischemic stroke

P Gelé, V Vingtdeux, C Potey, H Drobecq, A Ghestem… - Proteome Science, 2014 - Springer
Background Lipid lowering agent such as agonists of peroxisome proliferator-activated
receptors (PPAR) are suggested as neuroprotective agents and may protect from the …

Interference with peroxisome proliferator-activated receptor-γ in vascular smooth muscle causes baroreflex impairment and autonomic dysfunction

GR Borges, DA Morgan, P Ketsawatsomkron… - …, 2014 - Am Heart Assoc
S-P467L mice expressing dominant negative peroxisome proliferator-activated receptor-γ
selectively in vascular smooth muscle exhibit impaired vasodilation, augmented …

Attenuating Trigeminal Neuropathic Pain by Repurposing Pioglitazone and D-Cycloserine in the Novel Trigeminal Inflammatory Compression Mouse Model

DN Lyons - 2014 - uknowledge.uky.edu
Abstract Approximately 22% of the United States population suffers from a chronic orofacial
pain condition. One such condition is known as trigeminal neuropathic pain frequently …

Cannabinoids and Levodopa-Induced Dyskinesia

A Giuffrida, A Martinez - Levodopa-Induced Dyskinesia in Parkinson's …, 2014 - Springer
The endocannabinoid system modulates the release of excitatory and inhibitory
neurotransmitters in several brain areas implicated in motor control. Cannabinoid and …

[HTML][HTML] Interference with PPARγ in Vascular Smooth Muscle Causes Baroreflex Impairment and Autonomic Dysfunction

GR Borges, DA Morgan, P Ketsawatsomkron… - …, 2014 - ncbi.nlm.nih.gov
Abstract S-P467L mice expressing dominant negative Peroxisome Proliferator Activated
Receptor-γ selectively in vascular smooth muscle, exhibit impaired vasodilation, augmented …