The importance of the Basidiomycete Cryptococcus neoformans to human health has
stimulated its development as an experimental model for both basic physiology and …

A never-ending arms race drives coevolution between pathogens and hosts. In plants,
pathogen attacks invoke multiple layers of host immune responses. Many pathogens deliver …

Cryptococcus neoformans is a pathogenic basidiomycetous yeast responsible for more than
600,000 deaths each year. It occurs as two serotypes (A and D) representing two varieties …

Fungi can serve as highly tractable models for understanding genetic basis of sexual
development in multicellular organisms. Applying a reverse-genetic approach to advance …

Fungal genomes vary considerably in size and organization. The genome of Microsporidium
contains less than 3 Mb while the genomes of several Basidiomycetes and Ascomycetes …

An inducible RNA-silencing pathway, involving a single Dicer protein, DCL2, and a single
Argonaute protein, AGL2, was recently shown to serve as an effective antiviral defense …

Sexual reproduction is ubiquitous throughout the eukaryotic kingdom, but the capacity of
pathogenic fungi to undergo sexual reproduction has been a matter of intense debate …

The potential uses and therapeutic benefits of RNA interference (RNAi) are enormous.
Recent insights into RNAi technologies have highlighted their role in analyzing the functions …

How do cells distinguish normal genes from transposons? Although much has been learned
about RNAi-related RNA silencing pathways responsible for genome defense, this …

Quelling and DNA damage-induced small RNA (qiRNA) production are RNA interference
(RNAi)-related phenomenon from repetitive genomic loci in Neurospora. We have recently …