As marijuana use becomes legal in some states, the dominant public opinion is that
marijuana is a harmless source of mood alteration. Although the harms associated with …

Candidate gene× environment (G× E) interaction research tests the hypothesis that the
effects of some environmental variable (eg, childhood maltreatment) on some outcome …

Cannabis is the most commonly used illicit drug worldwide, with~ 5 million daily users
worldwide. Emerging evidence supports a number of associations between cannabis and …

Severe mental illness (SMI) is a broad category that includes schizophrenia, bipolar
disorder, and severe depression. Both genetic disposition and environmental exposures …

Converging epidemiological studies indicate that cannabis abuse during adolescence
increases the risk of developing psychosis and prefrontal cortex (PFC)-dependent cognitive …

Why the “nature versus nurture” debate persists despite widespread recognition that human
traits arise from the interaction of nature and nurture. If everyone now agrees that human …

Marijuana is the most widely used illicit drug among adolescents and young adults. Unique
cognitive, emotional, and social changes occur during this critical period of development …

Psychoactive substance and nonsubstance/behavioral addictions are major public health
concerns associated with significant societal cost. Adolescence is a period of dynamic …

The link between cannabis use and psychosis comprises three distinct relationships: acute
psychosis associated with cannabis intoxication; acute psychosis that lasts beyond the …

Although cannabis use is associated with an increased risk of developing psychosis, the
cannabis constituent cannabidiol (CBD) may have antipsychotic properties. This review …