Eukaryote genomes encode a surprisingly large number of noncoding transcripts. Around
two-thirds of human transcribed loci do not encode protein, and many are intergenic and …

The mouse gammaretroviruses associated with leukemogenesis are found in the classical
inbred mouse strains and in house mouse subspecies as infectious exogenous viruses …

Transcription of endogenous retroviruses (ERVs) is inhibited by de novo DNA methylation
during gametogenesis, a process initiated after birth in oocytes and at approximately …

The historical origins of classical laboratory mouse strains have led to a relatively limited
range of genetic and phenotypic variation, particularly for the study of behavior. Many recent …

Background: The heritable multifactorial etiology of human nonsyndromic cleft lip with or
without cleft palate (CL±P) is not understood. CL±P occurs in 15% of neonates in the …

Endogenous retroviruses (ERVs) represent ancestral sequences of modern retroviruses or
their extinct relatives. The majority of ERVs cluster alongside exogenous retroviruses into …

Several types of cancer in fish are caused by retroviruses, including those responsible for
major outbreaks of disease, such as walleye dermal sarcoma virus and salmon swim …

Structural variation is variation in structure of DNA regions affecting DNA sequence length
and/or orientation. It generally includes deletions, insertions, copy-number gains, inversions …

Absence epilepsy (AE) is a common type of genetic generalized epilepsy (GGE), particularly
in children. AE and GGE are complex genetic diseases with few causal variants identified to …

Transposable elements (TEs) make up a large proportion of mammalian genomes and are a
strong evolutionary force capable of rewiring regulatory networks and causing genome …