New perspectives on the synthesis and antichagasic activity of 3-alkoxy-1-alkyl-5-nitroindazoles

B Muro, F Reviriego, P Navarro, C Marín… - European Journal of …, 2014 - Elsevier
The synthesis and antiprotozoal activity of some 3-alkoxy-1-alkyl-(1, 4) and 3-alkoxy-1-(ω-
aminoalkyl)-5-nitroindazoles (2, 3, 5–8) against different morphological forms of …

Further insights into biological evaluation of new anti-Trypanosoma cruzi 5-nitroindazoles

C Fonseca-Berzal, JA Escario, VJ Arán… - Parasitology …, 2014 - Springer
Twelve molecules from a series of 35 new 5-nitroindazole derivatives, selected from a
successful primary screening on Trypanosoma cruzi epimastigotes, have been evaluated …

An expedient one-pot sequential five-component synthesis of highly substituted spiro-pyrrolidine heterocycles

D Gavaskar, R Raghunathan, ARS Babu - Tetrahedron Letters, 2014 - Elsevier
An expedient one-pot sequential five-component synthesis of highly substituted pyrrolidine
heterocycles involving [3+ 2]-cycloaddition of azomethine ylides as the key step is …

Antiprotozoan lead discovery by aligning dry and wet screening: prediction, synthesis, and biological assay of novel quinoxalinones

MAM Alho, Y Marrero-Ponce, SJ Barigye… - Bioorganic & medicinal …, 2014 - Elsevier
Protozoan parasites have been one of the most significant public health problems for
centuries and several human infections caused by them have massive global impact. Most …

[PDF][PDF] Escario, Vicente J. Arán & Alicia Gómez-Barrio

C Fonseca-Berzal, J Antonio - Parasitol Res, 2014 - researchgate.net
Twelve molecules from a series of 35 new 5-nitroindazole derivatives, selected from a
successful primary screening on Trypanosoma cruzi epimastigotes, have been evaluated …