The IL-23/IL-17 axis in psoriatic arthritis

E Suzuki, ED Mellins, ME Gershwin, FO Nestle… - Autoimmunity …, 2014 - Elsevier
Psoriatic arthritis (PsA) is an immune-mediated chronic inflammatory disease, affecting both
the skin and joints. Disease progression is associated with aberrant cytokine expression …

Role of NF‐κB in the pathogenesis of psoriasis elucidated by its staining in skin biopsy specimens

N Moorchung, JS Kulaar, M Chatterjee… - International Journal …, 2014 - Wiley Online Library
Background NF‐κB is a transcription factor belonging to the Re1 family, and it regulates the
activity of a large number of proinflammatory genes. Its role in psoriasis, which is a prototype …

Rotundarpene inhibits toll-like receptor 2 activation-induced production of inflammatory mediators in keratinocytes by suppressing the Akt and NF-κB pathways

YJ Kim, EB Jung, MS Lee, SJ Seo, MH Kim… - International …, 2014 - Elsevier
Microbial components have been shown to be involved in the pathogenesis of inflammatory
skin diseases. The extract of from the barks of Ilex rotunda Thunb has demonstrated anti …

Rotundarpene prevents TRAIL-induced apoptosis in human keratinocytes by suppressing the caspase-8-and Bid-pathways and the mitochondrial pathway

DH Lee, YJ Nam, YJ Kim, MW Lee, CS Lee - … -Schmiedeberg's archives of …, 2014 - Springer
The extract and hemiterpene glycosides of Ilex rotunda Thunb have demonstrated
antioxidant and anti-inflammatory effects. Nevertheless, the effect of rotundarpene on the …

Monoammonium glycyrrhizate suppresses tumor necrosis factor-α induced chemokine production in HMEC-1 cells, possibly by blocking the translocation of nuclear …

N Cao, T Chen, Z Guo, S Qin… - Canadian Journal of …, 2014 - cdnsciencepub.com
Monoammonim glycyrrhizate (MAG) derived from licorice has been shown to have anti-
inflammatory properties. Chemokines are vital inflammatory mediators that are involved with …