Regionally selective atrophy of subcortical structures in prodromal HD as revealed by statistical shape analysis
Huntington disease (HD) is a neurodegenerative disorder that involves preferential atrophy
in the striatal complex and related subcortical nuclei. In this article, which is based on a …
in the striatal complex and related subcortical nuclei. In this article, which is based on a …
Differential loss of thalamostriatal and corticostriatal input to striatal projection neuron types prior to overt motor symptoms in the Q140 knock-in mouse model of …
YP Deng, T Wong, JY Wan, A Reiner - Frontiers in Systems …, 2014 - frontiersin.org
Motor slowing and forebrain white matter loss have been reported in premanifest
Huntington's disease (HD) prior to substantial striatal neuron loss. These findings raise the …
Huntington's disease (HD) prior to substantial striatal neuron loss. These findings raise the …
Early decrease of type 1 cannabinoid receptor binding and phosphodiesterase 10A activity in vivo in R6/2 Huntington mice
Several lines of evidence imply early alterations in endocannabinoid and
phosphodiesterase 10A (PDE10A) signaling in Huntington disease (HD). Using [18 F] MK …
phosphodiesterase 10A (PDE10A) signaling in Huntington disease (HD). Using [18 F] MK …
Resolving pathobiological mechanisms relating to Huntington disease: gait, balance, and involuntary movements in mice with targeted ablation of striatal D1 …
Progressive cell loss is observed in the striatum, cerebral cortex, thalamus, hypothalamus,
subthalamic nucleus and hippocampus in Huntington disease. In the striatum, dopamine …
subthalamic nucleus and hippocampus in Huntington disease. In the striatum, dopamine …
The role of astrocytes in Huntington's disease
M Gray - Pathological Potential of Neuroglia: Possible New …, 2014 - Springer
Huntington's disease (HD) is a progressive autosomal dominant neurodegenerative
disorder characterized by psychiatric disturbances, cognitive impairment and choreiform …
disorder characterized by psychiatric disturbances, cognitive impairment and choreiform …
[图书][B] Role of striatal afferents in evolution of an animal model of Huntington's disease
A Boutet - 2014 - search.proquest.com
Huntington's disease (HD) is a neurodegenerative autosomal disorder caused by expanded
CAG repeats in the mutated Huntingtin gene. It is characterized by predominant loss of …
CAG repeats in the mutated Huntingtin gene. It is characterized by predominant loss of …
[PDF][PDF] Cell Replacement Therapy for Huntington's Disease: What We Have Learned from Post-mortem Analyses of Grafted Patients and Mice Models
G Cisbani - 2014 - collectionscanada.gc.ca
Huntington‟ s disease (HD) is a devastating autosomal dominant neurodegenerative
disorder which manifests because of a mutation in the huntingtin gene. It is characterized by …
disorder which manifests because of a mutation in the huntingtin gene. It is characterized by …
[引用][C] Mechanisms and efficacy of immunomodulatory therapies: neuroprotective effects in chronic inflammatory and degenerative diseases of the central nervous …
C Reick - 2014 - Dissertation, Bochum, Ruhr …