Obesity is frequently associated with chronic inflammation, metabolic and vascular
alterations which predispose to the development of the Metabolic Syndrome (MetS) …

Single nucleotide polymorphisms (SNPs) that cluster in the first intron of fat mass and
obesity associated (FTO) gene are associated obesity traits in genome-wide association …

To further understanding of the genetic basis of type 2 diabetes (T2D) susceptibility, we
aggregated published meta-analyses of genome-wide association studies (GWAS) …

Rigorous organization and quality control (QC) are necessary to facilitate successful
genome-wide association meta-analyses (GWAMAs) of statistics aggregated across multiple …

Until just a few years ago, the genetic determinants of obesity and metabolic syndrome were
largely unknown, with the exception of a few forms of monogenic extreme obesity. Since …

Obesity, characterized by excessive adiposity, is a risk factor for many metabolic
pathologies, such as type 2 diabetes mellitus (T2DM). Numerous studies have shown that …

BACKGROUND Endometriosis is a heritable common gynaecological condition influenced
by multiple genetic and environmental factors. Genome-wide association studies (GWASs) …

During the past 7 years, genome-wide association studies have shed light on the
contribution of common genomic variants to the genetic architecture of type 2 diabetes …

Coronary artery disease (CAD) is the leading cause of death and disability worldwide, and
its prevalence is expected to increase in the coming years. CAD events are caused by the …

In recent years, we've developed a much better grasp of the biological and other factors
associated with the development of obesity. Reflecting our evolving understanding of …