Nuclear Raf‐1 kinase regulates the CXCR5 promoter by associating with NFATc3 to drive retinoic acid‐induced leukemic cell differentiation

WM Geil, A Yen - The FEBS journal, 2014 - Wiley Online Library
Novel functions of signaling molecules have been revealed in studies of cancer stem cells.
Retinoic acid (RA) is an embryonic morphogen and stem cell regulator that controls the …

Phosphorylation of c-Cbl and p85 PI3K driven by all-trans retinoic acid and CD38 depends on Lyn kinase activity

J Congleton, M Shen, R MacDonald, F Malavasi… - Cellular signalling, 2014 - Elsevier
The leukocyte antigen CD38 is expressed after all-trans retinoic acid (ATRA) treatment in HL-
60 myelogenous leukemia cells and promotes induced myeloid differentiation when …

[HTML][HTML] Retinoic acid therapy resistance progresses from unilineage to bilineage in HL-60 leukemic blasts

HA Jensen, RP Bunaciu, CN Ibabao, R Myers… - PloS one, 2014 - journals.plos.org
Emergent resistance can be progressive and driven by global signaling aberrations. All-
trans retinoic acid (RA) is the standard therapeutic agent for acute promyelocytic leukemia …

Mechanistic aspects of lauryl gallate-induced differentiation and apoptosis in human acute myeloid leukemia cells

CLJ Teng, SM Han, WC Wu, CM Hsueh, JR Tsai… - Food and chemical …, 2014 - Elsevier
Lauryl gallate (LG) is a gallic acid derivative that has been widely used as an antioxidant
food additive. In this study, we examined the anticancer effects of LG on the human acute …

Retinaldehyde dehydrogenase 1 deficiency inhibits PPARγ-mediated bone loss and marrow adiposity

S Nallamshetty, PT Le, H Wang, MJ Issacsohn… - Bone, 2014 - Elsevier
PPARγ, a ligand-activated nuclear receptor, regulates fundamental aspects of bone
homeostasis and skeletal remodeling. PPARγ-activating anti-diabetic thiazolidinediones in …

Biological parameters influencing the human umbilical cord‐derived mesenchymal stem cells' response to retinoic acid

F Saraee, M Sagha, H Mohseni Kouchesfehani… - …, 2014 - Wiley Online Library
Human umbilical cord‐derived mesenchymal stem cells (HUCMSCs) are multipotent fetal
stem cells that differentiate into various cell lineages. In recent years, they have gained …

[HTML][HTML] Nardostachys chinensis induces the differentiation of human promyelocytic leukemic cells through the activation of the protein kinase C-dependent …

SM Ju, JG Kang, HO Pae, GS Lee… - International …, 2014 - spandidos-publications.com
The underground parts of Nardostachys chinensis (N. chinensis), which belongs the genus
Valerianaceae, have been used as sedative and analgesic agents in traditional Korean …

[PDF][PDF] Memory and learning enhancing activity of different extracts of roots of Vetiveria zizanioides

C Velmurugan, SK Shajahan, A Kumar… - … Journal of Novel …, 2014 - researchgate.net
The present study was undertaken to investigate the effects of Vetiveria zizanioides on
learning and memory in mice. Elevated plus maze were employed to test learning and …

[PDF][PDF] Retinoic Acid Therapy Resistance Progresses from Unilineage to Bilineage in HL-60

HA Jensen, RP Bunaciu, CN Ibabao, R Myers… - 2014 - academia.edu
Emergent resistance can be progressive and driven by global signaling aberrations. All-
trans retinoic acid (RA) is the standard therapeutic agent for acute promyelocytic leukemia …