Objective Stress precipitates and worsens not only asthma and atopic dermatitis but also
acute coronary syndromes (ACSs), which are associated with coronary inflammation …

Immune cells synthesize, store and secrete hormones, which are identical with the
hormones of the endocrine glands. These are: the POMC hormones (ACTH, endorphin), the …

Neuropeptides are involved in neurogenic inflammation where there is vasodilation and
plasma protein extravasion in response to this stimulus. Nerve growth factor (NGF) …

Mast cell (MC) activation disorders present with multiple symptoms including flushing,
pruritus, hypotension, gastrointestinal complaints, irritability, headaches …

Autism spectrum disorders (ASD) are neurodevelopmental disorders characterized by
defects in communication and social interactions, as well as stereotypic behaviors …

Mast cells play a key role in modulation of stress‐induced cutaneous inflammation. In this
study we investigate the impact of repeated exposure to stress on mast cell degranulation, in …

Microglia derive from mononuclear myeloid progenitors and are a major glial complement of
the central nervous system. When microglia are activated they secrete inflammatory …

Several recent studies suggest that peripheral corticotropin-releasing factor (CRF) receptor
type 1 (CRF1) and CRF2 have a counter regulatory action on gastrointestinal functions. We …

Abstract Background Chronic Fatigue Syndrome (CFS) is a neuroimmunoendocrine disease
affecting about 1% of the US population, mostly women. It is characterized by debilitating …

Data obtained from animal and human studies support the existence of mast cells (MC) in
the gastrointestinal (GI) tract, where they are considered important for the control of luminal …