Adrenergic receptors (AR) are G-protein-coupled receptors (GPCRs) that have a crucial role
in cardiac physiology in health and disease. Alpha1-ARs signal through G α q, and signaling …

Abstract Endothelin (ET-1) was initially identified as a potent vasoconstrictor contributing to
the maintenance of vascular rhythm. Later studies have implicated ET-1, when aberrantly up …

Aims Landiolol hydrochloride, an ultra-short-acting highly cardio-selective β-1 blocker, has
become useful for various medical problems. Recent studies have demonstrated that co …

Dilated cardiomyopathy (DCM) is a myocardial disease of unknown etiology with left
ventricular dilatation and impaired myocardial contractility leading to heart failure. It is …

S100A6, a 20 kDa, Ca2+-binding dimer with low basal cardiac expression, is upregulated in
the rat heart following infarction and forced expression of S100A6 in rat neonatal cardiac …

Aims Left ventricular assist devices (LVADs) are increasingly being used as life‐saving
therapy for end‐stage advanced heart failure. Diabetes is prevalent in advanced heart …

Résumé Objectif L'endothéline (ET) est une cible thérapeutique majeure dans les
pathologies cardiovasculaires et pulmonaires. Cette revue vise à synthétiser les différents …

There is evidence to suggest that endothelin (ET-1) is involved in the pathophysiology of
peripheral arterial disease (PAD), contributing to atherosclerotic narrowing of the lower limb …