The lung, while functioning as a gas exchange organ, encounters a large array of
environmental factors, including particulate matter, toxins, reactive oxygen species …

Although transplantation has been a standard medical practice for decades, marked
morbidity from the use of immunosuppressive drugs and poor long-term graft survival remain …

Invariant natural killer T (iNKT) cells are one of the innate lymphocytes that regulate
immunity, although it is still elusive how iNKT cells should be manipulated for transplant …

Introduction 3. Invariant Natural Killer T cells: modulatory cells at the bridge between innate
and adaptive immunity 3.1. The antigen specificity of iNKT cells: self and non-self glycolipids …

Background There have been extensive studies regarding which types of T lymphocytes are
involved in psoriasis vulgaris (PV). However, it has remained unclear which types of T …

Multiple sclerosis (MS) is an autoimmune disorder associated with neurological signs and
chronic inflammatory demyelination of the central nervous system (CNS). MS has been …

The idea of regulatory T cells (Tregs) lost its popularity during the 1980s and 1990s, since
immunologists failed to elucidate how the innate regulation of immunological reactions …

This editorial provides commentary on Hongo et al's (page 2467) demonstration that
transplant tolerance induction after recipient conditioning with total lymphoid irradiation …

The roles of natural killer (NK) T cells in intestinal immunity have not been sufficiently
investigated. The bowel possesses its own unique mucosal immune system, the gut …

In the early days of transplantation, all organs were retrieved from patients directly after
cardiorespiratory arrest [1]. Later, as it was acknowledged that death occurred from the …