Gene–environment interactions in severe mental illness

R Uher - Frontiers in psychiatry, 2014 - frontiersin.org
Severe mental illness (SMI) is a broad category that includes schizophrenia, bipolar
disorder, and severe depression. Both genetic disposition and environmental exposures …

Genetic relationships between schizophrenia, bipolar disorder, and schizoaffective disorder

AG Cardno, MJ Owen - Schizophrenia bulletin, 2014 - academic.oup.com
There is substantial evidence for partial overlap of genetic influences on schizophrenia and
bipolar disorder, with family, twin, and adoption studies showing a genetic correlation …

Genetics, cognition, and neurobiology of schizotypal personality: a review of the overlap with schizophrenia

U Ettinger, I Meyhöfer, M Steffens, M Wagner… - Frontiers in …, 2014 - frontiersin.org
Schizotypy refers to a set of temporally stable traits that are observed in the general
population and that resemble the signs and symptoms of schizophrenia. Here, we review …

[图书][B] Schizophrenia: A scientific delusion?

M Boyle - 2014 - taylorfrancis.com
First published in 2002. Schizophrenia: A Scientific Delusion?, first published in 1990, made
a very significant contribution to the debates on the concepts of schizophrenia and mental …

Second generation antipsychotic-induced obsessive-compulsive symptoms in schizophrenia: a review of the experimental literature

TM Fonseka, MA Richter, DJ Müller - Current psychiatry reports, 2014 - Springer
Second generation antipsychotics (SGAs) have been implicated in the de novo emergence
and exacerbation of obsessive-compulsive symptoms (OCS) in patients with schizophrenia …

The emerging molecular architecture of schizophrenia, polygenic risk scores and the clinical implications for GxE research

C Iyegbe, D Campbell, A Butler, O Ajnakina… - Social psychiatry and …, 2014 - Springer
Schizophrenia is a devastating mental disorder. The level of risk in the general population is
sustained by the persistence of social, environmental and biological factors, as well as their …

[HTML][HTML] Resting EEG in psychosis and at-risk populations—a possible endophenotype?

S Ranlund, J Nottage, M Shaikh, A Dutt… - Schizophrenia …, 2014 - Elsevier
Background Finding reliable endophenotypes for psychosis could lead to an improved
understanding of aetiology, and provide useful alternative phenotypes for genetic …

Interplay between childhood physical abuse and familial risk in the onset of psychotic disorders

HL Fisher, P McGuffin, J Boydell, P Fearon… - Schizophrenia …, 2014 - academic.oup.com
Background: Childhood abuse is considered one of the main environmental risk factors for
the development of psychotic symptoms and disorders. However, this association could be …

Evidence for disturbed insulin and growth hormone signaling as potential risk factors in the development of schizophrenia

NJM Van Beveren, E Schwarz, R Noll, PC Guest… - Translational …, 2014 - nature.com
Molecular abnormalities in metabolic, hormonal and immune pathways are present in
peripheral body fluids of a significant subgroup of schizophrenia patients. The authors have …

[图书][B] Complete psychology

I Albery, G Davey, C Sterling, A Field - 2014 - taylorfrancis.com
The new edition of Complete Psychology is the definitive undergraduate textbook. It not only
fits exactly with the very latest BPS curriculum and offers integrated web support for students …