Purification, characterization and crystallization of the human 80S ribosome

H Khatter, AG Myasnikov, L Mastio… - Nucleic acids …, 2014 - academic.oup.com
Ribosomes are key macromolecular protein synthesis machineries in the cell. Human
ribosomes have so far not been studied to atomic resolution because of their particularly …

The SBP2 protein central to selenoprotein synthesis contacts the human ribosome at expansion segment 7L of the 28S rRNA

O Kossinova, A Malygin, A Krol, G Karpova - Rna, 2014 - rnajournal.cshlp.org
SBP2 is a pivotal protein component in selenoprotein synthesis. It binds the SECIS stem–
loop in the 3′ UTR of selenoprotein mRNA and interacts with both the specialized …

[HTML][HTML] The CCA-end of P-tRNA contacts both the human RPL36AL and the A-site bound translation termination factor eRF1 at the peptidyl transferase center of the …

C Hountondji, K Bulygin, JB Créchet… - The Open …, 2014 - ncbi.nlm.nih.gov
We have demonstrated previously that the E-site specific protein RPL36AL present in
human ribosomes can be crosslinked with the CCA-end of a P-tRNA in situ. Here we report …