[HTML][HTML] Sleep deprivation reduces tear secretion and impairs the tear film

YB Lee, JW Koh, JY Hyon, WR Wee… - … & visual science, 2014 - tvst.arvojournals.org
Methods.: A total of 20 healthy male subjects with no ocular disease was recruited: 10 were
allocated to the SD group and 10 to the control group The 10 subjects in the SD group were …

Prednisolone-loaded nanocapsules as ocular drug delivery system: development, in vitro drug release and eye toxicity

T Katzer, P Chaves, A Bernardi… - Journal of …, 2014 - Taylor & Francis
Objective: To develop non-toxic aqueous ocular drug delivery systems containing
prednisolone by means of its nanoencapsulation. Materials and methods: Nanocapsules …

[HTML][HTML] Organization of lipids in the tear film: a molecular-level view

A Wizert, DR Iskander, L Cwiklik - PLoS One, 2014 - journals.plos.org
Biophysical properties of the tear film lipid layer are studied at the molecular level employing
coarse grain molecular dynamics (MD) simulations with a realistic model of the human tear …

Tear dynamics in healthy and dry eyes

CF Cerretani, CJ Radke - Current Eye Research, 2014 - Taylor & Francis
Purpose: Dry-eye disease, an increasingly prevalent ocular-surface disorder, significantly
alters tear physiology. Understanding the basic physics of tear dynamics in healthy and dry …

Investigation of tear osmolarity using the TearLab Osmolarity System in normal adults in Saudi Arabia

A Masmali, S Alrabiah, A Alharbi, GA El-Hiti… - Eye & Contact …, 2014 - journals.lww.com
Objectives: To investigate the repeatability and average tear osmolarity using the new lab-
on-chip TearLab technology device in normal subjects living in Saudi Arabia, a hot climate …

Thermal fluctuation based study of aqueous deficient dry eyes by non-invasive thermal imaging

M Azharuddin, SK Bera, H Datta… - Experimental eye research, 2014 - Elsevier
In this paper we have studied the thermal fluctuation patterns occurring at the ocular surface
of the left and right eyes for aqueous deficient dry eye (ADDE) patients and control subjects …

Prolonged exposure to loteprednol etabonate in human tear fluid and rabbit ocular tissues following topical ocular administration of Lotemax gel, 0.5%

S Glogowski, E Lowe, R Siou-Mermet… - Journal of ocular …, 2014 - liebertpub.com
Purpose: A new gel formulation containing loteprednol etabonate (LE), a C-20 ester
corticosteroid used to treat ocular inflammation, was developed to provide increased …

The definition and classification of dry eye disease

AJ Bron - Dry Eye: A Practical Approach, 2014 - Springer
Dry eye diseases are a group of disorders that share a mechanism by which tear
hyperosmolarity at the surface of the eye leads to inflammatory ocular surface damage. The …

Evaluation of ocular surface and tear film function following modified Hughes tarsoconjunctival flap procedure

A Klein‐Theyer, J Horwath‐Winter… - Acta …, 2014 - Wiley Online Library
Purpose: To evaluate ocular surface characteristics and tear film function following modified
Hughes flap for eyelid reconstruction. Methods: This is an institutional study including 18 …

New method for evaluation of early phase tear clearance by anterior segment optical coherence tomography

X Zheng, T Kamao, M Yamaguchi… - Acta …, 2014 - Wiley Online Library
Purpose To describe a new method of measuring early phase tear clearance by anterior
segment optical coherence tomography (AS‐OCT). Methods Sixty normal subjects were …