Inhibition of Na+/K+-ATPase induces hybrid cell death and enhanced sensitivity to chemotherapy in human glioblastoma cells

D Chen, M Song, O Mohamad, SP Yu - BMC cancer, 2014 - Springer
Background Glioblastoma multiforme (GBM) is very difficult to treat with conventional anti-
cancer/anti-apoptotic drugs. We tested the hypothesis that inhibition of Na+/K+-ATPase …

Ouabain induces endocytosis and degradation of tight junction proteins through ERK1/2-dependent pathways

R Rincon-Heredia, D Flores-Benitez… - Experimental cell …, 2014 - Elsevier
In addition to being a very well-known ion pump, Na+, K+-ATPase is a cell–cell adhesion
molecule and the receptor of digitalis, which transduces regulatory signals for cell adhesion …