XH Ye, ZB Bu, J Feng, L Peng, XB Liao, XL Zhu… - Molecular biology …, 2014 - Springer
The previous published data on the association between TP53 codon 72, intron 6, and intron 3 16 bp polymorphisms and lung cancer risk remained controversial. This meta …
Abstract p53 is a tumor suppressor gene, which is activated in response to several forms of cellular stress and exerts multiple antiproliferative functions, making it the most frequent …
X Wang, YZ Wang, KW Ma, X Chen, W Li - Oncology Research and …, 2014 - karger.com
Background/Aims: Etoposide and cisplatin (EP) chemotherapy is the most frequently used regimen in extensive-stage small-cell lung cancer (SCLC) patients, although the side effects …
A genome-wide association study revealed that a single nucleotide polymorphism, CLPTM1L-rs401681 (G> A), located at the 5p15. 33 locus was significantly associated with …
Aim: Systemic lupus erythematosus (SLE) is a systemic vasculitic disorder, with multiple genes involved in the disease pathogenesis. The p53 gene plays an important role in …
LIU Di, FAN Min - China Oncology, 2014 - china-oncology.com
Small cell lung cancer (SCLC) is an aggressive malignancy with fairly poor prognosis. Innovative treatment based on improved understanding of the genetic alterations of SCLC is …
Cel pracy: Toczeń rumieniowaty układowy (TRU) jest schorzeniem tkanki łącznej o przebiegu układowym. W patogenezie choroby uczestniczy kilka genów, spośród których …