Lung cancer risk in relation to TP53 codon 47 and codon 72 polymorphism in Bangladeshi population

MS Mostaid, MU Ahmed, MS Islam, MS Bin Sayeed… - Tumor Biology, 2014 - Springer
The objective of this study was to determine whether p53 codon 47 and codon 72
polymorphisms are associated with increased risk of lung cancer in Bangladeshi population …

Association between the TP53 polymorphisms and lung cancer risk: a meta-analysis

XH Ye, ZB Bu, J Feng, L Peng, XB Liao, XL Zhu… - Molecular biology …, 2014 - Springer
The previous published data on the association between TP53 codon 72, intron 6, and
intron 3 16 bp polymorphisms and lung cancer risk remained controversial. This meta …

小细胞肺癌分子遗传学研究进展

刘笛, 综述, 樊旼 - 中国癌症杂志, 2014 - china-oncology.com
小细胞肺癌(small cell lung cancer, SCLC) 恶性程度高, 预后差, 现有的靶向药物治疗基本无效,
迫切需要深入了解其分子特征从而筛选有效的治疗靶点. 二代测序等全基因组研究技术为肿瘤的 …

No evidence of correlation between p53 codon 72 G> C gene polymorphism and cancer risk in Indian population: a meta-analysis

RK Mandal, SS Yadav, AK Panda - Tumor Biology, 2014 - Springer
Abstract p53 is a tumor suppressor gene, which is activated in response to several forms of
cellular stress and exerts multiple antiproliferative functions, making it the most frequent …

MDM2 rs2279744 and TP53 rs1042522 polymorphisms associated with etoposide-and cisplatin-induced grade III/IV neutropenia in Chinese extensive-stage small …

X Wang, YZ Wang, KW Ma, X Chen, W Li - Oncology Research and …, 2014 - karger.com
Background/Aims: Etoposide and cisplatin (EP) chemotherapy is the most frequently used
regimen in extensive-stage small-cell lung cancer (SCLC) patients, although the side effects …

[PDF][PDF] Decreased risk of developing lung cancer in subjects carrying the CLPTM1L rs401681 (G> A) polymorphism: evidence from a meta-analysis

XL Zhang, XJ Zhang, YM Zhang, Q Zhang… - Genet. Mol …, 2014 - geneticsmr.com
A genome-wide association study revealed that a single nucleotide polymorphism,
CLPTM1L-rs401681 (G> A), located at the 5p15. 33 locus was significantly associated with …

p53 基因第72 位密码子多态性与肺癌临床病理特征及预后关系的Meta 分析

徐雄, 李丹, 徐斌, 李翀 - 临床肿瘤学杂志, 2014 - manu65.magtech.com.cn
目的系统评价p53 基因第72 位密码子的多态性与肺癌临床病理特征及预后的关系.
方法计算机检索PubMed, 中国知网, 维普, 万方等数据库, 收集有关p53 基因第72 …

[PDF][PDF] Association between p53 codon 72 polymorphism and systemic lupus erythematosus

M Nabavi, A Ghaderi, MJ Fattahi, N Danaie… - Reumatologia …, 2014 - termedia.pl
Aim: Systemic lupus erythematosus (SLE) is a systemic vasculitic disorder, with multiple
genes involved in the disease pathogenesis. The p53 gene plays an important role in …

Recent advances of molecular genetic characteristics of small cell lung cancer

LIU Di, FAN Min - China Oncology, 2014 - china-oncology.com
Small cell lung cancer (SCLC) is an aggressive malignancy with fairly poor prognosis.
Innovative treatment based on improved understanding of the genetic alterations of SCLC is …

Zależność między polimorfizmem kodonu 72 genu p53 a toczniem rumieniowatym układowym

M Nabavi, A Ghaderi, MJ Fattahi, N Danaie… - …, 2014 - reu.termedia.pl
Cel pracy: Toczeń rumieniowaty układowy (TRU) jest schorzeniem tkanki łącznej o
przebiegu układowym. W patogenezie choroby uczestniczy kilka genów, spośród których …