Adiposity and cancer risk: new mechanistic insights from epidemiology

AG Renehan, M Zwahlen, M Egger - Nature Reviews Cancer, 2015 - nature.com
Excess body adiposity, commonly expressed as body mass index (BMI), is a risk factor for
many common adult cancers. Over the past decade, epidemiological data have shown that …

Adiposity and risk of thyroid cancer: a systematic review and meta‐analysis

D Schmid, C Ricci, G Behrens, MF Leitzmann - Obesity reviews, 2015 - Wiley Online Library
Thyroid cancer incidence has increased rapidly over time, as has obesity prevalence. A link
between the two appears plausible, but the relation of adiposity to thyroid cancer remains …

Data resource profile: clinical practice research datalink (CPRD)

E Herrett, AM Gallagher, K Bhaskaran… - International journal …, 2015 - academic.oup.com
Abstract The Clinical Practice Research Datalink (CPRD) is an ongoing primary care
database of anonymised medical records from general practitioners, with coverage of over …

[HTML][HTML] Global, regional, and national comparative risk assessment of 79 behavioural, environmental and occupational, and metabolic risks or clusters of risks in 188 …

GBD 2013 Risk Factors Collaborators - Lancet (London, England …, 2015 - ncbi.nlm.nih.gov
Background The Global Burden of Disease, Injuries, and Risk Factor study 2013 (GBD
2013) is the first of a series of annual updates of the GBD. Risk factor quantification …

[HTML][HTML] Global burden of cancer attributable to high body-mass index in 2012: a population-based study

M Arnold, N Pandeya, G Byrnes, AG Renehan… - The lancet …, 2015 - thelancet.com
Background High body-mass index (BMI; defined as 25 kg/m 2 or greater) is associated with
increased risk of cancer. To inform public health policy and future research, we estimated …

[HTML][HTML] Anthropometric factors and endometrial cancer risk: a systematic review and dose–response meta-analysis of prospective studies

D Aune, DAN Rosenblatt, DSM Chan, S Vingeliene… - Annals of …, 2015 - Elsevier
Background Greater body mass index (BMI) has been convincingly related to increased
endometrial cancer risk, however, whether adiposity earlier in life or abdominal fatness is an …

Lifestyle and cancer risk

VA Katzke, R Kaaks, T Kühn - The Cancer Journal, 2015 - journals.lww.com
The global incidence of cancer is expected to increase substantially over the next decades.
This trend is very much driven by a rise in lifestyle-related cancers due to economic and …

Bariatric surgery in the United Kingdom: a cohort study of weight loss and clinical outcomes in routine clinical care

IJ Douglas, K Bhaskaran, RL Batterham… - PLoS medicine, 2015 - journals.plos.org
Background Bariatric surgery is becoming a more widespread treatment for obesity.
Comprehensive evidence of the long-term effects of contemporary surgery on a broad range …

[HTML][HTML] Insulin resistance and endometrial cancer risk: A systematic review and meta-analysis

AV Hernandez, V Pasupuleti, VA Benites-Zapata… - European journal of …, 2015 - Elsevier
Aim It has been suggested that chronic hyperinsulinemia from insulin resistance is involved
in the etiology of endometrial cancer (EC). We performed a systematic review and meta …

Body mass index, physical activity, and risk of adult meningioma and glioma: a meta-analysis

T Niedermaier, G Behrens, D Schmid, I Schlecht… - Neurology, 2015 - AAN Enterprises
Objective: Whether adiposity and lack of physical activity affect the risk for developing
meningioma and glioma is poorly understood. Our objective was to characterize these …